| 吴库生,霍霞.中国食管癌高、低发区土壤与植被类型比较研究[J].Chinese journal of Epidemiology,2008,29(1):44-47 |
| 中国食管癌高、低发区土壤与植被类型比较研究 |
| Comparative study on soil and vegetation characteristics from high-and low risk areas of esophageal cancer in China |
| Received:July 05, 2007 Revised:August 06, 2012 |
| DOI： |
| KeyWord: 食管肿瘤 地理信息系统 土壤类型 植被类型 土壤有机碳密度 |
| English Key Word: Norovirus Acute gastroenteritis Gene variation |
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| Abstract: |
| 目的 了解中国食管癌高、低发区土壤类型、植被类型及土壤有机碳密度(SOCD)的差异.方法 建立全国1990年代抽样研究地区食管癌死亡率数据库，在ArcGIS 9.1软件中制作相应研究地区的市、县界多边形电子地图并与疾病数据库链接，结合中国土壤及植被图运用多边形叠加分析的方法提取抽样地区土壤与植被类型，并计算土壤平均SOCD.比较食管癌高、低发区的土壤及植被类型及其分布比例，并对食管癌死亡率与相应地区平均SOCD进行等级相关分析.结果 中国食管癌高、低发区的土壤与植被类型均存在着明显的差异.男、女食管癌死亡率与100 cm及20 cm的平均SOCD均存在着负相关，相关系数分别是-0.504与0.575(男性，P值分别是0.004与0.001)及-0.487与-0.526(女性，P值分别为0.003与0.001).结论 食管癌死亡率的高低与所处地区的土壤、植被类型及SOCD均具有一定的相关性。 |
| English Abstract: |
| Objective To investigate the molecular characteristics of noroviruses detected in Beijing. Methods From January to March 2007,cases from both outbreaks and sporadic episodes of acute nonbacterial gastroenteritis were investigated in Beijing,and the fecal specimens of the patients were collected.Noroviruses were detected by a reverse transcription polymerase chain reaction(RT-PCR),and then the PCR products were cloned and sequenced.Results A total of 27 positive cases were identified as caused by noroviruses among the 38 patients with acute viral gastroenteritis,and four PCR products were randomly selected for further studies on sequencing.When comparing to the nucleotide sequences of norovirus reference strains from GenBank,the highest homology was found between the four isolates and the norovirus GⅡ/4 strains.The four strains isolated from Beijing were almost identical to the GⅡ/4 variants that causing epidemics in the Netherlands and in Japan with the homology of 97.8 %-98.5 % and 95.2 %-95.9 %,respectively.Phylogenetic analysis revealed that the four isolates were located at the same branch as the norovirus GⅡ/4 variants in Netherlands and Japan.Conclusion New norovirus GⅡ/4 variants were found in Beijing,and data from sequence analysis showed that the four isolates and the epidemic strains isolated from both the Netherlands and Japan in 2006 belonged to the same group of norovirus GⅡ/4. |
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