| 杨坤,周晓农.景观流行病学研究现状及其进展[J].Chinese journal of Epidemiology,2008,29(2):198-201 |
| 景观流行病学研究现状及其进展 |
| The study on status and development of landscape epidemiology |
| Received:June 28, 2007 Revised:September 12, 2012 |
| DOI： |
| KeyWord: 景观流行病学 研究 |
| English Key Word: Landscape epidemiology Study |
| FundProject:国家自然科学基金重大资助项目(30590373);江苏省卫生厅重点课题资助项目(H200625);江苏省社会发展基金资助项目(BS2007023) |
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| Abstract: |
| 人类的活动引起一系列传染病暴发、重现及改变地方病传播过程的研究越来越受到人们重视[1].一些土地使用的变化,包括森林砍伐、道路修建、农业活动、水坝修建、灌溉、海岸线退化、开矿等,其所带来的众多因素,如森林破碎化、病原体的输入、污染、贫穷、人口迁移等;加速了传染病的出现. |
| English Abstract: |
| Objective To establish a rapid method for testing drug sussceptibility on Mycobacterium tuberculosis.Methods Taking absolute Concentration method for drug susceptibility testing of M.tuberculosis as the"gold standard",we examined the drug-resistant of M.tuberculosis strain with nitrate reducrase assay (NRA) and the drug-resistant of M.tuberculosis germ in sputum with NRA. Results NRA and absolute concentration method was basically comparable with NRA susceptibility as 96.5% and the specificity was 100%,When comparing with traditional absolute concentration method, NRA could shorten the time about 3 weeks.Using NRA to test the drug-resistant of M.tuberculosis germ in sputum,its susceptibility was more than 66.7% and specificity was 100%,within 10-20 days. Conclusion NRA could be used as a rapid drug susceptibility testing on M.tuberculosis. |
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