| 武轶群,胡永华,任涛,吴涛,陶秋山,秦雪英,张奕,詹思延,曹卫华,李立明."降压0号"治疗原发性高血压的成本效果分析[J].Chinese journal of Epidemiology,2008,29(4):383-386 |
| "降压0号"治疗原发性高血压的成本效果分析 |
| Cost-effectiveness analysis on compound anti-hypertensive tablets for primary hypertension |
| Received:October 11, 2007 |
| DOI： |
| KeyWord: 高血压 药物经济学 降压0号 |
| English Key Word: Hypertension Pharmaco economies Compound anti-hypertensive tablets |
| FundProject:国家"十五"科技重点攻关资助项目(2001BAF03802) |
| Author Name | Affiliation | E-mail | | WU Yiqun | Department of Epidemiology and Biostatistics, Peking University Health Science Center, Beijing 100083, China | | | HU Yonghua | Department of Epidemiology and Biostatistics, Peking University Health Science Center, Beijing 100083, China | yhhu@bjmu.edu.cn | | REN Tao | Department of Epidemiology and Biostatistics, Peking University Health Science Center, Beijing 100083, China | | | WU Tao | Department of Epidemiology and Biostatistics, Peking University Health Science Center, Beijing 100083, China | | | TAO Qiushan | Department of Epidemiology and Biostatistics, Peking University Health Science Center, Beijing 100083, China | | | QIN Xueying | Department of Epidemiology and Biostatistics, Peking University Health Science Center, Beijing 100083, China | | | ZHANG Ying | Department of Epidemiology and Biostatistics, Peking University Health Science Center, Beijing 100083, China | | | ZHAN Siyuan | Department of Epidemiology and Biostatistics, Peking University Health Science Center, Beijing 100083, China | | | CAO Weihua | Department of Epidemiology and Biostatistics, Peking University Health Science Center, Beijing 100083, China | | | LI Liming | Department of Epidemiology and Biostatistics, Peking University Health Science Center, Beijing 100083, China | |
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| Abstract: |
| 目的 对"降压0号"治疗原发性高血压进行经济学评价,与常规降压药物进行比较探讨其成本效果.方法 采用流行病学实验研究的方法,选择两个社区内的高血压患者分别接受"降压0号"(0号组)和常规降压药物(常规组)治疗,长期随访记录血压和服药等情况,计算并比较两组的成本效果.结果 共收集研究对象2505人,0号组1529人,常规组976人;0号组和常规组的成本/效果比(C/E)分别为418.1和1057.7,在达到相同的血压达标率(100%达标)时,0号组比常规组节省639.6元,前者的成本效果比仅是后者的40%;以0号组为基准,常规组的增量成本效果比(△C/AE)为19 202.2,常规组与0号组相比,增加一定的药物费用,所增加的效果并不明显;两组成本效果相对于药品价格稳定.结论 "降压0号"能达到与常规降压药物相同的降压效果,而所需的费用仅为常规降压药物的40%。 |
| English Abstract: |
| Objective To compare the cost-effectiveness of two anti-hypertensive therapy regimens,Compound anti-hypertensive tablets and other common anti-hypertensive agents,in the treatment program of Primary Hypertension.Methods We conducted a cost-effectiveness analysis based on a community trial.Two communities'primary hypertensive patients were enrolled to receive different therapy drugs:Compound anti-hypertensive tablets(Group A)or other common anti-hypertensive agents(Group B).Blood pressure,medicine used,and adverse drug reactions were observed and recorded for one year,and then costeffectiveness ratio of the two groups and incremental ratio were calculated.We considered a 30%drug price fluctuating load to make the sensitivity analysis.Results 2505 cases were enrolled with 1529 cases in group A and 976 cases in group B.The cost-effectiveness ratios were 418.1 and 1057.7 for Group A and B respectively while the incremental cost-effectiveness of Group B vs.Group A was 19 202.2.The results were insensitive to variation in the costs of drugs over clinically reasonable ranges.Conclusion Compound anti-hypertensive tablets appeared to be relatively cost-effective when compared to common drugs for the treatment of primary hypertension. |
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