| 吴军华,季伟,丁云芳,陶云珍,骆亚丽,黄璐.苏州地区下呼吸道感染患儿卡他莫拉菌感染及耐药性分析[J].Chinese journal of Epidemiology,2008,29(8):844-845 |
| 苏州地区下呼吸道感染患儿卡他莫拉菌感染及耐药性分析 |
| Analysis on the prevalence and antibiotic resistance of Moraxella catarrhalis in children with lower respiratory tract infection in Suzhou |
| Received:February 20, 2008 |
| DOI： |
| KeyWord: 呼吸道感染 卡他莫拉菌 抗牛素耐药性 |
| English Key Word: espiratory tract infections Moraxella catarrhalis Antibiotic resistance |
| FundProject:贵州省科技基金及贵州省省长基金资助项目(2055) |
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| Abstract: |
| 了解苏州地区下呼吸道感染儿童卡他莫拉菌的感染情况及耐药性。1．资料与方法：对象为2006年6月至2007年5月苏州大学附属儿童医院住院下呼吸道感染患儿1446例（包括支气管肺炎、大叶性肺炎、急性喉-气管支气管炎、支气管哮喘合并支气管感染、毛细支气管炎、间质性肺炎），年龄为1月龄～14岁，其中男童883例（61．1％），女童563例（38．9％）。入院24h内用一次性导管经鼻腔送入7～10cm， |
| English Abstract: |
| Objective To identify the mortality-related factors in patients undergoing maintenance hemodialysis.Methods One hundred and seven long-term hemodialysis patients having suffered from chronic glomerulonephritis and received hemodialysis treatment in the hemodialysis center of the Friendship Hospital during February 1990 to February 2002 were selected to take part in a retrospective study. Survival analysis was done using Life Tables study. Cox regression analysis was used to find factors related to risk. Patients were divided into two groups according to the clinical value of the factors which showed statistical significance in Cox regression analysis. Survive rates were compared between two groups on Gehan test.Results Among the 107 patients, 22 died (15.3%)and 85 survived (84.7%)during the follow-up period. Cumulative survival rates of 5 years and 10 years were 79.91% and 64.36% respectively. Prognostic factors would include age (P 0.001), blood urea nitrogen (BUN, P=0.004), serum creatinine (SCr, P=0.001), value of plasma calcium multiplied by plasma phosphate (P=0.019), and KT/V (P=0.001), which were all tested during the third dialysis month. The Hazard Ratios (HR) were 1.107 (95% Confidence Interval,95% CI : 1.049- 1.168), 0.951(95% CI : 0.918- 0.984), 0.727(95% CI : 0.599- 0.883), 1.025(95% CI : 1.004- 1.046), and 0.013(95% CI : 0.001- 0.161), respectively. The survival rates between two groups were significant different (age≥60 years group vs 60 years group P=0.000 6, BUN≥ 28.6 mmol/L vs 28.6 mmol/L group P=0.041 5, SCr≥884 μmol/L vs 884 μmol/L group P=0.014 6, value of plasma calcium multiplied by plasma phosphate ≥40 vs 40 group P=0.046 4, KT/V≥ 1.30 vs 1.30 group P=0.021 5).Conclusions The mortality related prognostic factors of maintained hemodialysis patients seemed to include age, BUN, SCr, value of plasma calcium multiplied by plasma phosphate, and KT/V, which were all tested during the third dialysis month. Among them, age and the value of plasma calcium multiplied by plasma phosphate were risk factors of death, while the others were protective factors. |
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