| 杜飞,刘青恋,付清培,孙莉,和熬睿,关旭静,刘宇,王进,何惠,童文彬,覃志英,范文婧,李健,何吉兰,方刚.四川省乙型肝炎血清流行病学调查[J].Chinese journal of Epidemiology,2009,30(2):139-143 |
| 四川省乙型肝炎血清流行病学调查 |
| A seroepidemiologic analysis of hepatitis B in Sichuan province |
| Received:July 09, 2008 |
| DOI： |
| KeyWord: 乙型肝炎病毒 血清流行病学 调查 |
| English Key Word: Hepatitis B vLrus Seroepidemiology Survey |
| FundProject: |
| Author Name | Affiliation | E-mail | | DU Fei | Sichuan Province Center for Disease Control and Prevention, Chengdu 610041, China | | | LIU Qing-lian | Sichuan Province Center for Disease Control and Prevention, Chengdu 610041, China | | | FU Qing-pei | Sichuan Province Center for Disease Control and Prevention, Chengdu 610041, China | | | SUN Li | Sichuan Province Center for Disease Control and Prevention, Chengdu 610041, China | | | AO Rui | Sichuan Province Center for Disease Control and Prevention, Chengdu 610041, China | | | GUAN Xu-jing | Sichuan Province Center for Disease Control and Prevention, Chengdu 610041, China | | | LIU Yu | Sichuan Province Center for Disease Control and Prevention, Chengdu 610041, China | | | WANG Jin | Sichuan Province Center for Disease Control and Prevention, Chengdu 610041, China | | | HE Hui | Sichuan Province Center for Disease Control and Prevention, Chengdu 610041, China | | | TONG Wen-bin | Sichuan Province Center for Disease Control and Prevention, Chengdu 610041, China | | | QIN Zhi-ying | Sichuan Province Center for Disease Control and Prevention, Chengdu 610041, China | | | FAN Wen-jing | Sichuan Province Center for Disease Control and Prevention, Chengdu 610041, China | | | LI Jian | Sichuan Province Center for Disease Control and Prevention, Chengdu 610041, China | | | HE Ji-lan | Sichuan Province Center for Disease Control and Prevention, Chengdu 610041, China | | | FANG Gang | Sichuan Province Center for Disease Control and Prevention, Chengdu 610041, China | Email:gang_fang2008@163.com |
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| Abstract: |
| 了解乙型肝炎(乙肝)疫苗纳入儿童计划免疫后四川省乙肝病毒(HBV)感染情况。方法利用血清流行病学分析方法。按多阶段随机抽样方法，对四川省8个调查县(区)共14个调查点调查并采集静脉血标本2～4ml，共3806人份，用ELISA酶标法对标本进行HBsAg、抗-HBs、抗-HBc检测。 |
| English Abstract: |
| understand the changes of hepatitis B infection rates,before and after the hepatitis B vaccine Was included into EPI.and to evaluate the effect of immunization which would lead to the development of a more appropriate hepatitis B control strategy.Methods Seroepidemiologic method,with multi-section random sampling method were chosen.14 sites from 8 counties were involved.2-4 ml of the vein blood was drawn from all the individuals engaged in the study including 3806 samples.HBsAg,anti-HBs.anti-Hbe of the samples were tested with ELISA.Results Standardized positive rates of HBsAg and HBsAb were found as 7.05%and 29.77%respectively with the overall infection rate of HBV as 40.30%.The hepatitis B vaccine coverage of the children under 15 years was 70.73%and the positive rates for both HBsAg and anti-HBS were 2.62%and 56.68%.respectively.The coverage of hepatitis B vaccine among children under 3 years was 83.44%and the positive rates of both HBsAg and anti-HBs were 1.47%and 67.69%respectively.hepatitis B vaccine coverage of children under 3 years was 85.77%.with positive rates of HBsAg and anti-HBs as 1.78%and 75.44%respectively.Conclusion Results from our study revealed that since the introduction of hepatitis B vaccination,the prevalence rates of HBsAg and HBV infeetion had an obvious decline,especially in children aged under 15 years of old,suggesting that some changes had occurred in the epidemic characteristics ofhepatitis B in Sichuan. |
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