| 王憋杰,蒋岩.美国的艾滋病发病率监测[J].Chinese journal of Epidemiology,2009,30(2):199-202 |
| 美国的艾滋病发病率监测 |
| Surveillance on human immunodeficiency virus incidence in the United States |
| Received:April 24, 2008 |
| DOI： |
| KeyWord: 艾滋病病毒 发病率 监测 |
| English Key Word: Human immunodeficiency virus Incidence Surveillance |
| FundProject:国家科技部“十五”攻关课题资助项目[200lBA702804(A)] |
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| Abstract: |
| HIV发病率对于艾滋病的预防和控制至关重要。美国公共卫生领域的专家们研发了一种用于检测HIV新近感染者血清阳转的血清学检测规程，能够在群体水平上监测HIV发病率；基于此项技术，依托于较为完善的HIV/AIDS病例报告系统，美国于2005年开始在全国建立的HIV发病率监测系统逐渐趋于完善。 |
| English Abstract: |
| Objective To analyze the changes of the main clinic parameters in patients with benign prostate hyperplasia (BPH) treated by watchful waiting and to find out the risk factors contributing the progress of BPH. Methods According to the inclusion and exclusion criteria, 61 patients diagnosed as BPH were recruited in the group of watchful waiting. Data on IPSS, prostate volume, prostate specific antigen(PSA), maxium flow rate, average flow rate and residual urine volume during follow-up period of 24 months, were recorded. Results At 0, 12, 24 months, the IPSS, prostate volume (ml), PSA(ng/ml),maxium flow rate (ml/s) were 7±4, 4±3, 4±3 ; 33.0±9.0, 33.8±7.6, 30.9±6.8 ; 1.53±1.35,1.43±0.95, 1.22±0.99; 17.1±5.0, 17.2±6.1, 19.2±8.0, respectively. At the end of the 24-months follow-up, all observed parameters had a little improvement except the average prostate volume in this group. Of the 61 patients, 42(62%) progressed slowly or became better when comparing with baseline data of the study. Moreover, the difference between at 24-month and at baseline period, IPSS showed statistical significance (P＜0.0001) in t test. In the study of BPH progression risk factors by logistic regression analysis, prostate volume( P= 0.0910) and residual urine volume( P=0.0780) showed a trend of becoming the risk factors. Conclusion Our study showed that patients treated with watchful waiting had slow progression and majority of these patients did not need to alter their treatment options.Through data analysis, we noticed that the changes of data watchful waiting patients could help us to choose more precise and reasonable treatment option in clinical pratice.[ Key words ] Benign prostate hyperplasia; Prostate volume; Residual urine; Watchful waiting;Follow-up |
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