| 孙佳艺,赵冬,王薇,刘静,成君,刘军,秦兰萍.体重指数对10年累积高血压发病危险的预测作用[J].Chinese journal of Epidemiology,2009,30(5):435-438 |
| 体重指数对10年累积高血压发病危险的预测作用 |
| Association between body mass index and ten-year-accumulative-risk of hypertension |
| Received:December 17, 2008 |
| DOI： |
| KeyWord: 高血压 心血管疾病 体重指数 流行病学 |
| English Key Word: Hypertension Cardiovascular disease Body mass index Epidemiology |
| FundProject:北京市自然科学基金(7082019) |
| Author Name | Affiliation | | SUN Jia-yi | Department of Epidemiology, Beijing Anzhen Hospital Affiliated to the Capital University of Medical Science & Institute of Beijing Heart, Lung and Blood Vessel Diseases, Beijing 100029, China | | ZHAO Dong | Department of Epidemiology, Beijing Anzhen Hospital Affiliated to the Capital University of Medical Science & Institute of Beijing Heart, Lung and Blood Vessel Diseases, Beijing 100029, China | | WANG Wei | Department of Epidemiology, Beijing Anzhen Hospital Affiliated to the Capital University of Medical Science & Institute of Beijing Heart, Lung and Blood Vessel Diseases, Beijing 100029, China | | LIU Jing | Department of Epidemiology, Beijing Anzhen Hospital Affiliated to the Capital University of Medical Science & Institute of Beijing Heart, Lung and Blood Vessel Diseases, Beijing 100029, China | | CHENG Jun | Department of Epidemiology, Beijing Anzhen Hospital Affiliated to the Capital University of Medical Science & Institute of Beijing Heart, Lung and Blood Vessel Diseases, Beijing 100029, China | | LIU Jun | Department of Epidemiology, Beijing Anzhen Hospital Affiliated to the Capital University of Medical Science & Institute of Beijing Heart, Lung and Blood Vessel Diseases, Beijing 100029, China | | QIN Lan-ping | Department of Epidemiology, Beijing Anzhen Hospital Affiliated to the Capital University of Medical Science & Institute of Beijing Heart, Lung and Blood Vessel Diseases, Beijing 100029, China |
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| Abstract: |
| 目的探讨北京地区队列人群基线(1992年)BMI水平及10年(1992-2002年)BMI水平的变化与高血压发生的关系。方法采用前瞻性队列研究的方法，于1992年对北京大学社区和首都钢铁公司地区35～64岁人群进行基线心血管病危险因素调查，并持续10年对心血管病的发病情况进行随访。在2002年对相同人群再次进行了危险因素调查。两次调查资料完整，且对基线无高血压的2115人进行分析。结果调查的35～64岁人群10年高血压累积发病率为34。8%。随着基线BMI水平的增加，10年后高血压的累积发病率呈增加趋势(P<0。001)，男女两性的变化趋势一致。在45～54岁组和55～64岁组，随着基线BMI水平的增加，10年高血压的累积发病率也呈线性增加趋势(P<0。05)。多因素logistic回归分析显示，BMI≥28kg/m2组的高血压发病危险是BMI<24kg/m2组的3。6倍;10年BMI水平每增加1kg/m2，累积发生高血压的危险增加17。5%。1992年和2002年BMI均正常者中有22。0%的人发生高血压，1992年和2002年BMI均判为肥胖者中有56。3%的人发生高血压。结论BMI是高血压发病的一个独立危险因素，随着基线BMI水平的增加高血压的发病危险也增加。 |
| English Abstract: |
| Objective To explore the association between body mass index(BMI) and ten-year accumulative risk of hypertension.Methods A prospective study of relationship between blood pressure and other traditional risk factors was carried out in a cohort with 2115 people aged 35-64 years old involved, in 1992 and 2002. The association between baseline BMI level and a ten-year accumulative risk of hypertension was analyzed.Results The ten-year accumulative incidence rate of hypertension was 34.8%, and increased with the elevated baseline BMI level in both genders (P<0.001). Similar changing trends were observed in both age groups of 45-54 year and 55-64 year olds (P<0.05). Multivariable OR (95%CI) of accumulative incident hypertension in the highest BMI tertile(≥128 kg/m2) was 3.569 higher (2.559 to 4.977) when compared to the lowest (<24 kg/m2). The ten-year accumulative risk of hypertension increased 17.5% with elevation of baseline BMI level by 1 kg/m2. The ten-year accumulative incidence rate of hypertension was 22.0% in the subjects with normal BMI and 56.3% in those with obesity, both in 1992 and 2002.Conclusion BMI appeared to be an independent risk factor for hypertension, and the risk of incident hypertension increased with elevated BMI level. |
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