Abstract
牛瑞,邵明举,刘波,黄晓春,车晓文,王伟.咳嗽变异性哮喘在不明原因慢性咳嗽中的患病率及相关因素分析[J].Chinese journal of Epidemiology,2009,30(5):511-513
咳嗽变异性哮喘在不明原因慢性咳嗽中的患病率及相关因素分析
Research on morbidity and relative factors of cough variant asthma among patients with chronic cough syndrome
Received:August 18, 2008  
DOI:
KeyWord: 咳嗽变异性哮喘  患病率  相关因素
English Key Word: Cough variant asthma  Prevalence rate  Correlation factors
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Author NameAffiliationE-mail
NIU Rui Department of Respiratory, Second Hospital of Shandong University, Jinan 250033, China  
SHAO Ming-ju Department of Respiratory, Second Hospital of Shandong University, Jinan 250033, China  
LIU Bo Department of Respiratory, Second Hospital of Shandong University, Jinan 250033, China  
HUANG Xiao-chun Department of Respiratory, Second Hospital of Shandong University, Jinan 250033, China  
CHE Xiao-wen Department of Respiratory, Second Hospital of Shandong University, Jinan 250033, China  
WANG Wei Department of Respiratory, Second Hospital of Shandong University, Jinan 250033, China ww8160@163.com 
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Abstract:
      目的调查咳嗽变异性哮喘(CVA)在不明原因慢性咳嗽中的患病率并进行相关因素分析。方法对入选的慢性咳嗽患者经过详细询问病史和体格检查、胸部X线检查、血嗜酸粒细胞分类计数、肺通气功能和组织胺激发试验或支气管扩张试验,根据检查结果做出CVA的明确诊断;并对CVA患者填写相关因素调查问卷。结果473例慢性咳嗽患者中,确诊CVA95例(20。08%),其中男44例(46。31%)、女51例(53。68%)。相关因素分析显示CVA与多种因素有关。结论CVA以春秋两季多发,与过敏史、哮喘家族史相关,可由呼吸道感染、吸入油烟或刺激性气体、运动及劳累诱发。
English Abstract:
      Objective To study the morbidity of cough variant asthma (CVA) among patients with chronic cough syndrome and its relative risk factors.Methods Patients were recruited with detailed history on their illness. Data were collected on physical examination, chest X-ray, eosinophil cell counts, pulmonary ventilation with histamine stimulating test and bronchi dilation test. According to available data, diagnosis of CVA was confirmed and the relative factors Questionnaire form was completed for each patient.Results Among 473 patients with chronic cough, 95 (44 male and 51 female) were confirmed to be CVA (20.08%). Analysis of the relative factors suggested that CVA was associated with multiple factors. Morbidity of CVA was associated with season, personal histories on allergy and family history on asthma, CVA could be induced by upper respiratory tract infection, inhale of oil vapor, acrimony air, over-burdened physical exercises etc.Conclusion For patients with chronic cough symptom, clear diagnosis of CVA, avoid of passable risk factors and timely medical intervention when necessary, would be helpful in controlling clinical courses and improving the prognosis of the disease.
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