湖南省美沙酮维持治疗患者维持治疗时间现状及影响因素分析

李杏莉; 谭红专; 孙振球; 张恒; 陈梦施; 欧秋英

Abstract

李杏莉,谭红专,孙振球,张恒,陈梦施,欧秋英.湖南省美沙酮维持治疗患者维持治疗时间现状及影响因素分析[J].Chinese journal of Epidemiology,2009,30(7):672-675

湖南省美沙酮维持治疗患者维持治疗时间现状及影响因素分析

Study on the time of retention and related influencing factors of patients receiving methadone maintenance treatment in Hunan province

Received:October 23, 2008

DOI：10.3760/cma.j.issn.0254-6450.2009.07.005

KeyWord: 美沙酮维持治疗维持率治疗时间影响因素

English Key Word: Methadone maintenance treatment Retention rate Treatment time Influencing factors

FundProject:第四轮中国全球基金仲英艾滋病项目(20080R47)

Author Name	Affiliation	E-mail
Li Xing1i	410078,长沙,中南大学公共卫生学院
TAN Hongzhuan	410078,长沙,中南大学公共卫生学院	tanhz99@qq.com
SUN Zhenqiu	410078,长沙,中南大学公共卫生学院
ZHANG Heng	410078,长沙,中南大学公共卫生学院
CHEN Mengshi	410078,长沙,中南大学公共卫生学院
YIN qiuying	湖南省疾病预防控制中心

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Abstract:

目的了解湖南省美沙酮维持治疗患者维持治疗时间的现状以及影响因素。方法收集湖南省前两批开诊的7个美沙酮门诊接受治疗的海洛因成瘾者的一般情况以及日常治疗信息, 分析患者治疗时间、治疗维持率, 探索影响维持治疗时间的因素。结果湖南省7个美沙酮门诊维持治疗患者6个月的维持治疗率为72.06％, 1年的维持治疗率为49.65％。高、低剂量组的患者6个月的维持治疗率分别为85.03％、68.03％;1年的维持治疗率分别为60.48％、46.28％;差异均有统计学意义。在随访观察1年中, HIV阳性和HIV阴性患者的平均美沙酮维持治疗时间分别为9.46个月和8.62个月, 差异有统计学意义。高剂量组患者、非注射吸毒方式患者、高年龄患者、HIV阳性患者更易于坚持美沙酮维持治疗。结论湖南省美沙酮维持治疗门诊6个月和1年的维持治疗率与全国水平相似。维持治疗时间的长短与剂量、吸毒方式、年龄及HIV感染状况有关。

English Abstract:

Objective to explore the current situation and related influencing factors Oil the retention time of patients receiving methadone maintenance treatment(MMT).Methods Information On basic situation and daily treatment of the patients were collected from the 7 MMT clinics opened in the pro.two batch in Hunan province.Retention rate and influencing factors were analyzed.Results (1)The retention rates after 6 and l 2 months of MMT became 72.06%and 49.65%respectively.(2)The retention rates of high-dosage group and low-dosage group were 85.03%and 68.03%after 6 months on MMT program while became 60.48%and 46.28%after l 2 months of MMT respectively.(3)The mean retention time of HIV+patients and HIV-patients were 9.46 months and 8.62 months respectively during the 12 months follow-up observation。showing a significant difference.(4)Patients who took large dose methadone, did not share needles, at older age or HIV+。were prone to keep MMT at a long period. Conclusion The retention rates for 6 months and 12 months in the MMT program in Hunan rovince were similar to the national data.Dose, type of drug abuse, age and HIV status were related to the period of retention.

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