| 舒同,曾龙驿,穆攀伟,王曼曼,张国超,陈燕铭.持续皮下胰岛素输注和胰岛素每日多点注射治疗2型糖尿病的成本效果分析[J].Chinese journal of Epidemiology,2009,30(7):737-739 |
| 持续皮下胰岛素输注和胰岛素每日多点注射治疗2型糖尿病的成本效果分析 |
| Cost-effectiveness analysis on continuous subcutaneous insulin infusion and multi—point daily insulin injections in the treatment program of type 2 diabetes |
| Received:December 24, 2008 |
| DOI：10.3760/cma.j.issn.0254-6450.2009.07.024 |
| KeyWord: 2型糖尿病 持续皮下胰岛素输注 胰岛素每日多点注射 成本效果分析 |
| English Key Word: Type 2 diabetes Continuous subcutaneous insulin infusion Multi-point daily insulin injections Cost—effectiveness analysis |
| FundProject: |
| Author Name | Affiliation | E-mail | | SHU Jiong | Department of Endocrinology, The third Affiliated Hospital,SUN Yat-sen University, Guangzhou 510630, China | | | ZENG Longyi | Department of Endocrinology, The third Affiliated Hospital,SUN Yat-sen University, Guangzhou 510630, China | LY.zeng@medmail.com.cn | | MU Panwei | Department of Endocrinology, The third Affiliated Hospital,SUN Yat-sen University, Guangzhou 510630, China | | | WANG Manman | Department of Endocrinology, The third Affiliated Hospital,SUN Yat-sen University, Guangzhou 510630, China | | | ZHANG Guochao | Department of Endocrinology, The third Affiliated Hospital,SUN Yat-sen University, Guangzhou 510630, China | | | CHEN YanMing | Department of Endocrinology, The third Affiliated Hospital,SUN Yat-sen University, Guangzhou 510630, China | |
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| Abstract: |
| 目的 比较新人院的2型糖尿病患者使用持续皮下胰岛素输注(CSⅡ)和胰岛素每日多点注射(MDI)控制2型糖尿病血糖达标的成本效果。方法 回顾性分析86例使用CSll方案和103例使用MDI方案控制m糖的新入院2型糖尿病患者, 观察时间为2周。运用药物经济学中的成本效果分析法对两种治疗方案进行评价。结果 治疗2周后, CS 11组与MDI组患者m糖控制有效率相似, 差异无统计学意义(P>O.05);CSII组低血糖反应发生率及夜间低血糖发生率较MDI组明显降低(P<0.05), 其他不良反应发生率相似;CSII方案成本(元/人)比MDI方案低(1478.34 VS.1620.46), 差异有统计学意义(P<0.05)：成本效果比(C/E)显示CS 11组为15.07, MDI组为16.34, 差异无统计学意义(P>O.05);再以成本较低的CSlI组方案为参照, 增量的成本效果比(AC/AE)MDI组为129.20。结论 使用CSll方案控制新入院2型糖尿病患者治疗的成本效益较MDI方案好, CSII方案是住院期间胰岛素强化治疗的较优选择。 |
| English Abstract: |
| Obiective To observe the cost.effectiveness of using continuous subcutaneous insulin infusion(CSⅡ)and multi.point daily insulin injections(MDI)in controlling blood SHgar in the newly hospitalized type 2 diabetes patients.Methods Retrospective analysis on 86 cases taking CS II and 1 03 cases using MDI on a‘blood sugar control program’among the newly hospitalized patients with type 2 diabetes.The period for observation was 2 weeks, using cost.effectiveness analysis Methods to evaluate the two treatment programs.Results After two weeks of treatment.the effectiveness in the control of blood sugar in CS 11 group was similar to the MDI group, with no significant difference(PP<0.05).The cost-eriectiveness ratios(C/E) were 15.07 in the CS 1I group。and 16.34 in the MDI group, with no significant difierence(P>0.05).In order to further reduce the cost of CS II group as a reference.the incremental cost-effectiveness ratio(AC/AE)ofthe MDI group was 129.20.Conclusion Costs.effective ofthe CS 11 program was better than the MDI one in treating the newly hospitalized patients with type 2 diabetes。suggesting that CS II program might be a better choice for hospitals to carry on an intensive insulin therapy program. |
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