中国大陆2009年早期确诊的420例甲型H1N1流感病例流行病学特征分析

李亚品; 钱全; 方立群; 杨红; 魏茂提; 高燕; 杨华; 张勇; 曹务春

Abstract

李亚品,钱全,方立群,杨红,魏茂提,高燕,杨华,张勇,曹务春.中国大陆2009年早期确诊的420例甲型H1N1流感病例流行病学特征分析[J].Chinese journal of Epidemiology,2009,30(11):1102-1105

中国大陆2009年早期确诊的420例甲型H1N1流感病例流行病学特征分析

Epidemiological characteristics of 420 influenza A(H1NI)cases confirmed jn the early stage of the epidemic in mainland China

Received:July 03, 2009

DOI：

KeyWord: 甲型H1N1流感流行病学特征

English Key Word: Influenza A(H1N1) Epidemiological characteristics

FundProject:国家"十-五"科技重大专项(2008ZXl0004-012, 2009ZXl0004-720)|国家"863"高技术研究发展计划(2007AAl2Z240)

Author Name	Affiliation	E-mail
LI Ya-pin	State Key Laboratory of Pathogen and Biosecurity
QIAN Quan	State Key Laboratory of Pathogen and Biosecurity
FANG Li-qun	State Key Laboratory of Pathogen and Biosecurity
YANG Hong	State Key Laboratory of Pathogen and Biosecurity
WEI Mao-ti	State Key Laboratory of Pathogen and Biosecurity
GAO Yan	State Key Laboratory of Pathogen and Biosecurity
YANG Hua	Academy of Military Medical Science Institute of Microbiology and Epidemiology, Beijing 100071, China
ZHANG Yong	Academy of Military Medical Science Institute of Microbiology and Epidemiology, Beijing 100071, China
CAO Wu-chun	北京师范大学, 北京, 100071	caowc@nic.bmi.ac.cn

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Abstract:

目的了解中国大陆2009年早期(5月11日至6月22日)确诊的甲型HINl流感病例的流行病学特征.方法应用描述性流行病学方法对中国大陆2009年早期确诊的420例甲型HINI流感病例的年龄、性别、来源、主要症状、潜伏期等流行病学特征进行分析.结果中国大陆早期诊断的甲型HlNl流感病例中输入性病例占总病例数的77.8%,主要由美国、加拿大、澳大利亚三个国家输入,占中国大陆总输人性病例的90%|所有患者中男性占53%,平均年龄22岁(22.2岁±14.9岁)|早期确诊的甲型H1N1病例以发热(81%)、咳嗽(40%)、咽痛(35%)等症状为主|输人性病例从入境到发病平均2.5 d±1.9 d(1-ll d),二代甲型H1N1流感病例的平均潜伏期为4.3 d±1.7 d(1-8 d).结论中国早期确诊的甲型H1NI流感病例以输入性病例为主|其性别构成与输入国相类似,而年龄构成不同|早期确诊患者以上呼吸道感染症状为主|输人性病例从入境到发病平均2.5 d±1.9 d(1-1l d),二代病例平均潜伏期为4.3 d-4-1.7 d(1～8 d).

English Abstract:

Objective To describe the epidemical characteristiCS of A(H1N1)influenza identified in the early stage(from May ll to June 22, 2009)of the epidemic.in mainland China.Methods Epidemical characteristics of420 confirmed A(HlNl)influenza cases reponed from May 11 to June 22, 2009 were analyzed descriptively, including the distribution of age, sex.source of infection.main symptoms and incubation period. Results AtotaI of 77.8%early cases in mainland China were imposed from othel"cotmtries.Three countries including America.Canada and Australia were attributed to 90%of the imposed cases.Most of the cases were from 6 months to 73 years old.with 94%ofthem under 50 years.Most of the symptoms would include fever(8 l%), cough(40%)and sore throat(35%).The mean incubation period of second.generation cases was 4.3(4.2± 1.5)davs.Conclusion Imposed cases dominated the total cases in the early stage of the epidemic had similar gender distribution of those from exporting countries.Fever, cough and sore throat were the three main symptoms manifested in influenza cases.2.5±1.9(1-11)days Was found in imported cases between the day of board and the onset of symptoms.The incubation period Was 4.3±1.7(1-8)days among the secondary cases.

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