Abstract
张允平,张志翔,沈默宇,邓向群,丁钟琴,王劲松.77 1例脑梗死住院患者糖脂代谢异常的研究[J].Chinese journal of Epidemiology,2009,30(11):1194-1197
77 1例脑梗死住院患者糖脂代谢异常的研究
Study on abnormal glucose and lipid metabolism among 771 in-patients with ischemic stroke
Received:March 24, 2009  
DOI:
KeyWord: 脑梗死  糖脂代谢  口服葡萄糖耐量试验
English Key Word: Ischemic stroke  Glucose and lipid metabolism  Oral glucose tolerance test
FundProject:
Author NameAffiliationE-mail
ZHANG Yun-ping Department of Endocrinology, Changzhou No.2 Hospital Affiliated to Nanjing Medical University, Changzhou 2l3003, China  
ZHANG Zhi-xiang Department of Endocrinology, Changzhou No.2 Hospital Affiliated to Nanjing Medical University, Changzhou 2l3003, China  
SHEN Mo-yu Department of Endocrinology, Changzhou No.2 Hospital Affiliated to Nanjing Medical University, Changzhou 2l3003, China  
DENG Xiang-qun Department of Endocrinology, Changzhou No.2 Hospital Affiliated to Nanjing Medical University, Changzhou 2l3003, China  
DING Zhong-qin Department of Endocrinology, Changzhou No.2 Hospital Affiliated to Nanjing Medical University, Changzhou 2l3003, China  
WANG Jin-song 扬州大学医学院流行病学教研室 yzdewjs@163.com 
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Abstract:
      目的探讨脑梗死患者糖脂代谢异常的状况.方法收集常州巾-第二人民医院神经内科和内分泌科2007年4月至2008年4月住院的脑梗死患者771例,未确诊糖尿病的对象均进行口服葡萄糖耐量试验(OGTT)以判断糖代谢状况.结果脑梗死住院患者中确诊糖尿病的患者为41.8%,糖代谢受损者有23.4%,总的糖代谢异常患病牢65.2%.若不进行OGTT,单纯依靠空腹m糖进行诊断,将有58.5%的糖尿病患者被漏诊.同时发现脑梗死患者中存在脂代谢异常,主要表现为高TG和低HDL-C.结论脑梗死住院患者中大多数合并糖脂代谢异常,需要通过OGTT及时准确地发现合并糖代谢异常的患者,以减少脑梗死再发.
English Abstract:
      Objective To study the epidemiological characteristics of abnormal glucose and lipid metabolism in in.patients with ischemic stroke. Methods A total number of 77 l in-patients with ischemic stroke.hospitalized in the Department of Neurology/ Endocrinology from Changzhou No.2 HospitaJ from April 2007 to April 2008 were enrolled in this study.Aher identifying the condition of glucose metabolism.all diagnosis- undetermined patients received oral glucose tolerance test.Results Among in-patients with ischemic stroke.4 1.8%of the patients were finally diagnosed as diabetes.with 23.4%classified as'impaired glucose tolerance'.The prevalence of'abnormal glucose metabolism'was 65.2%in total.If diabetes in the in-patients with ischemic stroke was diagnosed only by fast plasma glucose instead of oral glucose tolerance test.58.5%diabetic patients would have been misdiagnosed.Abnormal lipid metabolism existed in inpatients with cerebral ischemic stroke were noticed.These abnormalities of lipid metabolism were mainly consisting of increased triglyceride and decreased HDL-C cholesterol.Conclusion The majority of in-patients with ischemic stroke appeared to have had abnormal glucose and lipid metabolism.It seemed necessary to promptly and correctly diagnose these patients with abnormal glucose metabolism by oral glucose tolerance test to reduce the chances of developing the recurrence of stroke.
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