| 俞浩,郭志荣,胡晓抒,周正元,武鸣.代谢综合征评分与Framingham风险评分预测心血管疾病的比较[J].Chinese journal of Epidemiology,2010,31(2):208-212 |
| 代谢综合征评分与Framingham风险评分预测心血管疾病的比较 |
| A comparison between the metabolic syndrome score and the Framingham risk score in the prediction of cardiovascular disease |
| Received:August 12, 2009 |
| DOI： |
| KeyWord: 代谢综合征 心血管疾病 Framingham风险评分 危险性评估 |
| English Key Word: Metabolic syndrome Cardiovascular disease Framinghanl risk score Risk assessment |
| FundProject:卫生部科学研究基金(WⅪ2004-2-014) |
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| Abstract: |
| 目的比较代谢综合征(MS)评分与Framingham 10年发病风险评分(FRS)预测心血管疾病(CVD)的能力。方法参照FRS评分模式，对MS组分分层赋值，建立MS评分。以“江苏省多代谢异常和代谢综合征防治队列研究”中随访时间满5年的人群为研究对象，用Cox比例风险模型和受试者T.作特征曲线(R0c)比较MS评分与FRS对CVD的预测能力。结果Ms组分评分后预测CVD的能力显著提高[MS评5子/MS的ROC曲线下面积(AUC):0.70/0.65，P<0.05，灵敏度:80.5％/74.4％3；单个调整MS和FRS的组分，结果显示仅去除年龄后，FRS预测CVD发病危险的AUC明显下降，为0.65(P结论加入年龄因素的MS评分预测CVD的能力达到FRS相同水平，是实用的预测CVD工具。 |
| English Abstract: |
| Objective To compare metabolic syndrome(MS)score with the 10-year-Framingham risk score(FRS)to predict the occurrence of cardiovascular disease(CVD).Methods MS score for prediction of CVD was developed based on the 10.year FRS.COX proportional hazard model and receiver-operating characteristic(ROC)curves were used to compare the predictive effects，based on data from a cohort study 013.the prevention of multipIle metabolic disorders and MS in Jiangsu province.Results Area under the cnrve(AUC)increased after changing MS components into continuous variables.AUC of MS score/MS components aggregation was 0.70/0.65.P<0.05 and sensitivity of MS score/MS components aggregation was 80.5％/74.4％for a given specificity.After mutually adjusted risk factors of MS score and the FRS，when age Was exclusively excluded，AUC of the FRS decreased from 0.78 to 0.65(PConclusion The new developed MS score with age included Was a valid tool for predicting CVD and its predictive ability Was as good as theFRS. |
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