北京地区8280名正常人群和代谢综合征患者的年龄相关糖尿病患病风险研究

马靖; 冯洁; 吕泽平; 黄慧; 万刚; 黄金; 张建佚; 杨双雨; 杜建玲; 郭立新; 杨泽

Abstract

马靖,冯洁,吕泽平,黄慧,万刚,黄金,张建佚,杨双雨,杜建玲,郭立新,杨泽.北京地区8280名正常人群和代谢综合征患者的年龄相关糖尿病患病风险研究[J].Chinese journal of Epidemiology,2010,31(3):241-244

北京地区8280名正常人群和代谢综合征患者的年龄相关糖尿病患病风险研究

Study on the risk of age·related diabetes mellitus among 8280 cases with metabolic syndrome patientsandnormalpersonsinBeijing

Received:September 28, 2009

DOI：

KeyWord: 代谢综合征糖尿病空腹血糖调节受损患病风险

English Key Word: Metabolic syndrome Diabetes mellitus Impaired fasting glycaemia Risk of diabetes mellitus

FundProject:国家自然科学基金(30972709，30671110)；国家重点基础研究发展规划项目(973计划)(2006CB503901)

Author Name	Affiliation	E-mail
MA Jing	Beijing Hospital, Institute of Geriatrics, Ministry of Health, Beqing 100730, China The First Affiliated Hospital ofDalian Medical University
FENG Jig	Beijing Hospital, Institute of Geriatrics, Ministry of Health, Beqing 100730, China Peking Union Medical College, Chinese Academy of Medical Sciences
LV Ze-ping	Guangxi Jiangbin Hospital
HUANG Hui	Guangxi Jiangbin Hospital
WAN Gang	Beijing Hospital, Institute of Geriatrics, Ministry of Health, Beqing 100730, China
HUANG Jin	Beijing Hospital, Institute of Geriatrics, Ministry of Health, Beqing 100730, China
ZHANG Jian-yi	Beijing Hospital, Institute of Geriatrics, Ministry of Health, Beqing 100730, China
YANG Shuang-yu	Beijing Hospital, Institute of Geriatrics, Ministry of Health, Beqing 100730, China
DU Jian-ling	The First Affiliated Hospital ofDalian Medical University
GUO Li-xin	Beijing Hospital, Institute of Geriatrics, Ministry of Health, Beqing 100730, China
YANG Ze	Beijing Hospital, Institute of Geriatrics, Ministry of Health, Beqing 100730, China	yangze016@yahoo.com.cn

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Abstract:

目的探讨年龄对正常人群及代谢综合征(MS)患者糖尿病患病风险的影响。方法按照随机抽样原则，选取北京地区年龄在20岁以上、录入资料完整的8280人作为研究对象(男性4873人，女性3407人)。将总体人群分为正常人群组和MS患者组，并以年龄每10岁为组距对研究对象进行年龄分组，分别计算各组血糖正常者、空腹血糖调节受损(IFG)和糖尿病(DM)患者的人数及其构成比。结果(1)总体人群、正常人群和MS患者各自的不同年龄组IFG及DM患病风险不同(P<0．05)；(2)总体人群中IFG患病率随年龄递增，DM患病率在20。79岁人群中随年龄递增，80岁以上人群中降低，经趋势f检验，P<0．05；(3)正常人群中IFG患病率与DM患病率均在20一79岁人群中随年龄递增，80岁以上人群中降低；(4)MS患者中IFG患病率在20一69岁人群中随年龄递增，70岁及以上人群中降低，DM患病率未见随年龄变化趋势。结论(1)在正常人群中IFG和DM患病率随年龄增加，年龄越大，患病人数越多，表现出高龄群体高患病风险的增龄特点；(2)Ms患者中IFG亦表现出增龄特点，但是DM的患病风险与年龄无关；(3)无论是否伴有¨s，70。79岁年龄段均为DM的高患病风险阶段。

English Abstract:

Objective To investigate the impact of age on patients with metabolic syndrome (MS) and normal persons. Methods Data was gathered from 8280 persons including 4873 males and 3407 females who were randomly selected. All subjects were devided into normal group and MS group. According to the interval of ten years, the subjects were devided into seven age groups, to calculate the difference of impaired fasting glycaemia (IFG) between patients with diabetes mellitus (DM) and normal people, as well as the related portions. Results (1) The risk of IFG and DM appeared to be different among age groups among the target subjects as well as in the normal and the MS groups (P<0.05). (2) Among the whole subjects, the overall prevalence of IFG was increasing with age. The prevalence of DM had an increasing trend with age augment in 20-79 years group, whereas a decreasing trend appeared in people over 80 years of age. (3) For normal persons, the prevalence of IFG and DM were all increasing with age augment in 20-79 years group, and then decreasing with age augment in the over-80-years group. (4)For MS patients, the prevalence of IFG had an increasing trend with age augment in 20-69 years group, whereas a decreasing trend appeared in people over 70 years of age. There was no tendency of variation with age augment in DM.Conclusions (1) For normal persons, high prevalence rates of IFG and DM were correlated to age augment, especially in senior persons. (2) For MS patients, high prevalence of IFG was also correlated to age augment, but no association between prevalence of DM and age augment was seen. (3)Age from 70 to 79 years appeared to be in high risk with MS.

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