Abstract
张翠彩,李秀文,聂一新,崔志刚,蒋秀高.多位点可变数目串联重复序列分析对致病性钩端螺旋体分型的研究[J].Chinese journal of Epidemiology,2010,31(3):349-350
多位点可变数目串联重复序列分析对致病性钩端螺旋体分型的研究
Application of multiple-locus variable-number tandemrepeat analysis (MLVA) on molecular typing of Leptospira interrogans
Received:September 21, 2009  
DOI:
KeyWord: 钩端螺旋体  基因分型  多位点可变数目串联重复序列分析
English Key Word: Leptospira interrogans  Genotyping  Multiple-locus variable-number tandem repeat analysis(MLVA)
FundProject:卫生行业科研专项(200802016);国家高科技研究发展计划(863)(2006AA02Z176)
Author NameAffiliationE-mail
ZHANG Cui-cai National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China  
LI Xiu-wen National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China  
NIE Yi-xin National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China  
CUI Zhi-gang National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China  
JIANG Xiu-gao National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China jiangxiugao@icdc.cn 
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Abstract:
      钩端螺旋体(钩体)病是一种自然疫源性疾病。近年来以可变数目串联重复序列(variable number of tandem repeats,VNTR)为基础的分型方法。逐渐被应用于分子流行病学研究中。本研究选取我国致病性钩端螺旋体15群15型参考菌株,初步探讨多位点可变数目串联重复序列分析(MI、硝)在钩体病分子流行病学研究中的应用价值。
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