| 周芳,傅君芬,王春林,梁黎.睡眠时间与肥胖儿童代谢综合征的关系[J].Chinese journal of Epidemiology,2010,31(4):455-458 |
| 睡眠时间与肥胖儿童代谢综合征的关系 |
| Relationship between sleep duration and metabolic syndrome in obese children |
| Received:September 03, 2009 |
| DOI：10.3760/cma.j.issn.0254-6450.2010.04.022 |
| KeyWord: 肥胖儿童|代谢综合征|睡眠时间 |
| English Key Word: Obese children|Metabolic syndrome|Sleep duration |
FundProject:浙江省自然科学基金(Y2080047);
卫生部科学研究基金-浙江省医药卫生重大科技计划项目(WKJ2008-2-026);
浙江省科技厅藿大科技项目(2008c03002-1);
“十一五”国家科技支撑计划(2009BAl808001) |
| Author Name | Affiliation | E-mail | | Zhou Fang | Department of Endocrinology, Children's Hospital of Zhejiang University School of Medicine, Hangzhou 310003, China | | | Fu Junfen | Department of Endocrinology, Children's Hospital of Zhejiang University School of Medicine, Hangzhou 310003, China | fjf68@yahoo.com.cn | | Wang Chunlin | Department of Endocrinology, Children's Hospital of Zhejiang University School of Medicine, Hangzhou 310003, China | | | Liang Li | Department of Endocrinology, Children's Hospital of Zhejiang University School of Medicine, Hangzhou 310003, China | |
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| Abstract: |
| 目的 探讨睡眠时间与肥胖儿童代谢综合征(MS)的关系。方法 对311例肥胖儿童分别记录睡眠时间及测定空腹血糖(FBG)、血脂、血压、BMI等有关MS的诊断指标, 并根据睡眠时间(<8h、8h～、9h～、≥10h)分为4组进行比较分析, 将MS作为反应变量、睡眠时间作为自变量, 正常BMI儿童作为对照, 进行多分类无序反应变量的logistic回归分析结果每天睡眠时间<8h的肥胖儿童与每天睡眠时间≥10h的肥胖儿童比较, 各项MS组分测定值(BMI、血压、血脂、FBG)差异有统计学意义(P<0.05), MS及血压、空腹胰岛素、BMI异常(≥30kg/m2)发生率的差异也有统计学意义(P<0.05); 通过多分类无序反应变量的logistic回归分析发现睡眠时间减少是肥胖儿童发生MS的危险因素。结论 睡眠不足是肥胖儿童发生MS的重要影响因素。 |
| English Abstract: |
| Objective To investigate the relationship between sleep duration and metabolic syndrome in obese children. Methods Sleep time was recorded and metabolic syndrome (MS) diagnostic criteria as blood pressure, body mass index (BMI) were measured among 311 obese children. The children were divided into 4 groups by sleep time while normal-weight children served as the control group. A disorderly multi-classification logistic regression method was used. Results Statistically, significant differences were found in the levels of BMI, blood pressure, fasting blood glucose and postprandial 2h glucose and the incidence rates of abnormality on MS, blood pressure, fasting instalim. and BMI≥30kg/m2 between the group with daily sleep time less than 8h and the group with daily sleep time no less than 10h(P<0.05). Date from logistic regression analysis revealed that the reduction of sleep time was the risk factor of MS in obese children. Conclusion Insufticient sleep could greatly contribute to the occurrence of MS in obese children. |
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