黄芳,郭婧,崔淑娟,吕燕宁,高志勇,李伟红,严寒秋,曲梅,石伟先,卢桂兰,张新,张代涛,田丽丽,钱海坤,杨鹏,庞星火,王全意.北京市甲型H1N1流感病毒病原学监测分析[J].Chinese journal of Epidemiology,2010,31(5):494-496 |
北京市甲型H1N1流感病毒病原学监测分析 |
Etiological characteristics of influenza A (H1N1) 2009 virus in Beijing |
Received:January 12, 2010 |
DOI:10.3760/cma.j.issn.0254-6450.2010.05.004 |
KeyWord: 甲型H1N1流感病毒 荧光定量PCR 病原学 |
English Key Word: Influenza A (H1N1) 2009 Real-time PCR Etiology |
FundProject:欧盟第6框架基金(015396);上海市气象局科技开发项目(YJ201101);公益性行业科研专项(GYHY201206027) |
Author Name | Affiliation | E-mail | HUANG Fang | Beijing Centerfor Disease Control and Preuention, Beijing 100013, China | | CUO Jing | Beijing Centerfor Disease Control and Preuention, Beijing 100013, China | | CUI Shujuan | Beijing Centerfor Disease Control and Preuention, Beijing 100013, China | | LV Yan-ring | Beijing Centerfor Disease Control and Preuention, Beijing 100013, China | | GAO Zhi-yong | Beijing Centerfor Disease Control and Preuention, Beijing 100013, China | | LI Wei-bong | Beijing Centerfor Disease Control and Preuention, Beijing 100013, China | | YAN Han-qiu | Beijing Centerfor Disease Control and Preuention, Beijing 100013, China | | QU Mei | Beijing Centerfor Disease Control and Preuention, Beijing 100013, China | | SHI Wei-xian | Beijing Centerfor Disease Control and Preuention, Beijing 100013, China | | LU Gui-fern | Beijing Centerfor Disease Control and Preuention, Beijing 100013, China | | ZHANG Xin | Beijing Centerfor Disease Control and Preuention, Beijing 100013, China | | ZHANG Dai-tao | Beijing Centerfor Disease Control and Preuention, Beijing 100013, China | | TIAN Li-li | Beijing Centerfor Disease Control and Preuention, Beijing 100013, China | | QIAN Hai-kun | Beijing Centerfor Disease Control and Preuention, Beijing 100013, China | | YANG Peng | Beijing Centerfor Disease Control and Preuention, Beijing 100013, China | | PANG Xing-hua | Beijing Centerfor Disease Control and Preuention, Beijing 100013, China | | WANG Quan-yi | Beijing Centerfor Disease Control and Preuention, Beijing 100013, China | bjcdcxm@126.Com |
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Abstract: |
目的 分析北京市2009年5一12月甲型HINl流感病毒检测结果,探讨流感大流行时期甲型H1N1流感病原流行病学特征。方法 2009年5月1日至2009年12月27日,共采集101852份咽拭子样本,北京市传染病网络实验室利用荧光定量PCR方法检测,并做统计分析。结果 101852份检测样本中,甲型H1N1流感病毒核酸阳性9843份,总阳性率为9.66%,其中5—6月阳性率为2.85%,7—8月阳性率为3.32%,9—10月阳性率为8.35%。11月阳性率为29.67%,12月阳性率为24.33%。可疑病例排查阳性率为8.40%,病例密切接触者阳性率为4.75%,门诊流感样病例(ILI)阳性率为11.46%,聚集性发热病例及其他病例阳性率为7.33%。年龄分布以5~14岁和15~24岁年龄段为主,男女性别构成比为1.5:1。结论 北京市2009年5—11月甲型H1N1流感病毒感染呈持续上升,12月呈下降趋势,具有一定的流行病学特征。 |
English Abstract: |
Objective To analyze the results of detection on influenza A (H1N1)2009 virus in Beijing from May 2009 to December 2009 and to understand the epidemiologic characteristics during the pandemic period.Methods The study was conducted from the May 1 to December 27,2009.A total of 101 852 throat swab samples were detected with the real-time RT PCR assay by the Beijing Network Laboratory.Data was statistically analyzed.Results 9843 samples showed influenza A (H1Ni)2009 positive,with an overall positive rate as 9.66%.In terms of the positive rates,they were 2.85% from May to June,3.32% from July to August and 8.35% from September to October.The peak month fell in November (29.67%)and December (24.33%).The positive rates among the following subpopulations were:8.40% among the suspected cases,4.75% among close contact cases,11.46% among the influenza-like illness cases and 7.33% among the cluster cases with fever.Positive cases mainly fell in age groups 5-14 and 15-24.The ratio of male to female was 1.5:1.Conclusion During the pandemic period of influenza A (H1N1)2009,positive cases gradually increased during May to November but slowly decreasing in December. |
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