| 何海燕,周明珠,陆丽霞,吴佳英,干静,陈伟,刘振国.帕金森病患者家庭照顾者负担及相关影响因素分析[J].Chinese journal of Epidemiology,2010,31(6):692-695 |
| 帕金森病患者家庭照顾者负担及相关影响因素分析 |
| Burden and related factors among care-takers of patients with Parkinson's disease |
| Received:October 10, 2009 |
| DOI：10.3760/cma.j.issn.0254-6450.2010.06.021 |
| KeyWord: 帕金森病 照顾者负担 生活质量 |
| English Key Word: Parkinson's disease Caregiver burden Quality of life |
| FundProject:上海市科委纳米专项基金(0952nm03700);上海市基础研究重点项目(09JC1411000);上海市教育委员会科研创新重点项目(10ZZ72) |
| Author Name | Affiliation | E-mail | | HE Hai-yan | Department of Neurology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai200092, China | | | ZHOU Ming-zhu | Department of Neurology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai200092, China | | | LU Li-xia | Department of Neurology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai200092, China | | | WU Jia-ying | Department of Neurology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai200092, China | | | GAN Jing | Department of Neurology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai200092, China | | | CHEN Wei | Department of Neurology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai200092, China | | | LIU Zhen-guo | Department of Neurology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai200092, China | zhenguoliu2004@yahoo.com.cn |
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| Abstract: |
| 目的 调查帕金森病(PD)患者家庭照顾者的负担及生活质量,分析其主要影响因素.方法 采用照顾者负担问卷(CBI)评估115例PD患者主要照顾者的负担,同时应用统一PD评分量表(UPDRS)、Hoehn-Yahr分级(H-Y分级)、日常生活能力量表(ADL)、PD生活质量量表(PDQ-39)、Hamilton抑郁量表(HAMD)、Hamilton焦虑量表(HAMA)、蒙特利尔认知评估量表(MoCA)、简易智能量表(MMSE)等评分,对115例原发性PD患者的疾病严重度、情绪、认知功能及生活质量等进行评估.采用Spearman相关分析及多元逐步同归分析方法分析影响照顾者负担的主要因素.结果 CBI的主要影响因素为患者ADL(β=-0.813,t=-6.26:5,P=0.000)、PDQ-39(β=0.285,t=4.256,P=0.000)及照顾者年龄(β3=0.327,t=3.107,P=0.002).结论 PD患者家庭照顾者负担受多方面因素影响,应引起社会各界的关注,给予针对性干预措施. |
| English Abstract: |
| Objective To assess the impact on caretaker who looked after patients with Parkinson's disease(PD) and to identify the main factors related to their burden.Methods 115 consecutive pairs of PD patients and their caretakers were included.Caregiver Burden Inventory (CBI) was used to assess the burden of PD on the caretakers.Patients were evaluated by neurologists using the United Parkinson's Disease Rating Scale(UPDRS),the Hoehn and Yahr Scale(H-Y Scale),the Activity of Daily Liring Scale(ADL),the Parkinson's Disease Quesnonnaire(PDQ-39),the Hamilton Depression Rating Scale(HAMD),the Hamilton Anxiety Rating Scale(HAMA),the Montreal Cognitive Assessment(MoCA)and the Mini-mental State Examination(MMSE).Multiple linear stepwise regression models were fired to ascertain the factors linked to the CBI.Results Based on multiple linear stepwise regression analysis,ADL(β=-0.813,t=-6.265,P=0.000)and PDQ-39(β=0.285,t=4.256,P=0.000)of patients and the age ofcaretakers(β=0.327,t=3.107,P=0.002)proved to be the main predictors of CBI.Conclusion Many factors might comprehensively affct the burden of PD on caretakers of the patients.Attention needs to be given to the early identification of factors that generating stress on 1iveretakers in order to improve their quality of life. |
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