Abstract
梁瑞英,叶荣伟,李宏田,任爱国,刘建蒙.浙江省嘉兴地区初孕妇女自然流产状况研究[J].Chinese journal of Epidemiology,2010,31(7):755-758
浙江省嘉兴地区初孕妇女自然流产状况研究
Study on the current status of spontaneous abortion of primigravid women in Jiaxing of Zhejiang province, China
Received:February 04, 2010  
DOI:
KeyWord: 自然流产  孕周别流产率  初孕妇女  命表
English Key Word: Spontaneous abortion  Miscarriage rate by gestation  Primigravid women  Life table
FundProject:教育部留学回国人员科研启动基金
Author NameAffiliationE-mail
LIANG Rui-ying Institute of Reproductive and Child Health, Peking University, Beijing 100191, China  
YE Rong-wei Institute of Reproductive and Child Health, Peking University, Beijing 100191, China  
LI Hong-tian Institute of Reproductive and Child Health, Peking University, Beijing 100191, China  
REN Ai-guo Institute of Reproductive and Child Health, Peking University, Beijing 100191, China  
LIU Jian-meng Institute of Reproductive and Child Health, Peking University, Beijing 100191, China liujm@pku.edu.cn 
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Abstract:
      目的了解浙江省嘉兴地区初孕妇女自然流产状况及分布特征.方法 资料来源于北京大学生育健康研究所嘉兴地区围产保健监测及自然流产数据.研究对象为嘉兴地区1993-1995年登记的准备结婚及生育并最终怀孕(不包括人工流产、宫外孕及葡萄胎)的初孕妇女14769名.结果嘉兴地区初孕妇女自然流产率为9.8%(1454/14769,95%CI:9.3~10.3),平均妊娠诊断孕周为(7.6±2.1)周,平均流产孕周为(10.1±3.1)周.早期(≤12周)自然流产率为7.3%(95%CI:6.8~7.7),占总流产的73.7%.流产集中发生在8~13周,占37.7%.经多因素Cox回归分析,生育年龄≥30岁、农民、文化程度高者自然流产率较高.结论 嘉兴地区初孕妇女自然流产率高于国内其他地区;自然流产主要发生在8~13孕周.
English Abstract:
      Objective To study the current status of spontaneous abortion of primigravid women in Jiaxing areas of Zhejiang province of China. Methods We analyzed the data from both perinatal healthcare surveillance program and spontaneous abortion, collected in Jiaxing areas by the Institute of Reproductive and Child Health, Peking University. The study population consisted of 14 769 primigravid women (excluding induced abortion, ectopic pregnancy and molar pregnancy as outcomes) attempting to become pregnant who registered between 1993 and 1995. Results 1454 spontaneous abortion cases were identified, with the spontaneous abortion rate as 9.8% (95% CI:9.3%-10.3%). The mean gestational weeks at pregnancy diagnosis were 7.6±2.1 weeks, the mean gestational weeks at miscarriage were (10.1±3.1) weeks and the incidence of first-trimester (≤12 weeks) spontaneous abortion was 7.3%(95%CI: 6.8%-7.7%), accounting for 73.7% of all the spontaneous abortion cases. A peak for risk of miscarriage was around 8-13 weeks, accounting for 37.7% of all spontaneous abortion. The observed multiple Cox regression model showed that increased spontaneous abortion rates were observed in women with age at pregnancy ≥30, being peasants and with higher education level. Conclusion The spontaneous abortion rate of primigravid women in Jiaxing areas was higher than in other areas of China. The maximum occurrence of spontaneous abortions was during period of 8-13 gestation weeks.
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