云南边境地区登革1型病毒非结构蛋白编码区序列测定及进化分析

苑述友; 蔡学敏; 张富强; 邱薇; 李刚山; 刘华; 尹革芬; 李作生; 郑颖; 王双印; 张海林; 范泉水

Abstract

苑述友,蔡学敏,张富强,邱薇,李刚山,刘华,尹革芬,李作生,郑颖,王双印,张海林,范泉水.云南边境地区登革1型病毒非结构蛋白编码区序列测定及进化分析[J].Chinese journal of Epidemiology,2010,31(7):830-831

云南边境地区登革1型病毒非结构蛋白编码区序列测定及进化分析

Sequencing and phylogenetic analysis for non-structure protein coding region of dengue virus from yunnan border

Received:October 12, 2010

DOI：

KeyWord: 登革1型病毒非结构蛋白编码区进化分析

English Key Word: Dengue virus serotypes 1 Non-stucture protein Coding region Phylogenetic analysis

FundProject:军队"十一五"科技攻关项目(08G034);中国博士后科学基金项目(20090451579)

Author Name	Affiliation	E-mail
YUAN Shu-you	College of Animal Science, Yunnan Agricultural University, Kunming 650223, China The Military Medical Institute of Chengdu Military Area The Military Medical Institute of Chengdu Military Area
CAI Xue-min	The Military Medical Institute of Chengdu Military Area
ZHANG Fu-qiang	The Military Medical Institute of Chengdu Military Area
QIU Wei	The Military Medical Institute of Chengdu Military Area
LI Gang-shan	College of Animal Science, Yunnan Agricultural University, Kunming 650223, China The Military Medical Institute of Chengdu Military Area
LIU Hua	College of Animal Science, Yunnan Agricultural University, Kunming 650223, China The Military Medical Institute of Chengdu Military Area
YIN Ge-fen	College of Animal Science, Yunnan Agricultural University, Kunming 650223, China
LI Zuo-sheng	College of Animal Science, Yunnan Agricultural University, Kunming 650223, China
ZHENG Ying	College of Animal Science, Yunnan Agricultural University, Kunming 650223, China
WANG Shuang-yin	The Military Medical Institute of Chengdu Military Area
ZHANG Hai-lin	Yunnan Institute of Endenic Disease Control and Frevention
FAN Quan-shui	The Military Medical Institute of Chengdu Military Area	fqs168@126.com

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Abstract:

登革病毒有4个血清型，可引起登革热和登革出血热／登革休克综合征。登革病毒包括5’和3’非编码区(UTR)及一个单一的开放阅读框(ORF)，该ORF编码一个聚蛋白前体，经蛋白酶裂解加工成3种结构蛋白(C、PrM和E)和7种非结构蛋白(NSl、NS2A、NS2B、NS3、Ns4A、NS4B和NS5)n】。我国云南省边境与登革热流行区的缅甸和泰国等东南亚国家接壤，自然生态环境又与东南亚地区相似，曾从云南省白纹伊蚊中分离到登革3型和4型病毒乜J】。

English Abstract:

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