Abstract
刘梅,赵冰,张建辉,丁燕,胡建伟,许锬,佟伟军,张永红.急性脑出血患者入院时血压与住院期间临床结局的关系[J].Chinese journal of Epidemiology,2010,31(9):1070-1071
急性脑出血患者入院时血压与住院期间临床结局的关系
Relationship between blood pressure at admission and clinical outcome during hospitalization among patients with intracerebral hemorrhage
Received:May 13, 2010  
DOI:
KeyWord: 脑出血  血压  临床结局
English Key Word: Intracerebral hemorrhage  Blood pressure  Clinical outcome
FundProject:国家自然科学基金(30972531)
Author NameAffiliationE-mail
LIU Mei Department of Epidemiology, School of Radiation Medicine and Public Health, Medical College of Soochow University, Suzhou 215123, China  
ZHAO Bing Department of Neurology, First Renmin Hospital of Kerqin District, Tongliao  
ZHANG Jian-hui Department of Neurology, Tongliao Municipal Hospital  
DING Yan Department of Neurology, Tongliao Municipal Hospital  
HU Jian-wei Department of Epidemiology, School of Radiation Medicine and Public Health, Medical College of Soochow University, Suzhou 215123, China  
XU Tan Department of Epidemiology, School of Radiation Medicine and Public Health, Medical College of Soochow University, Suzhou 215123, China  
TONG Wei-jun Department of Epidemiology, School of Radiation Medicine and Public Health, Medical College of Soochow University, Suzhou 215123, China  
ZHANG Yong-hong Department of Epidemiology, School of Radiation Medicine and Public Health, Medical College of Soochow University, Suzhou 215123, China yhzhang@suda.edu.cn 
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Abstract:
      脑卒中是导致居民死亡和残疾的主要原因[1].在我国脑卒中分别占男性和女性总死亡的21.6%和20.8%[2].与西方人群相比,中国人群出血性脑卒中的发病率更高[2].出血性脑卒中具有病死率高、致残率高及复发率高的特点[4].高血压是脑卒中发病最重要的危险因素.一些研究结果表明血压的升高与脑出血不良结局呈正相关[5,6];另一些研究则显示血压与脑出血不良结局之间呈"U"形关联[7,8]或者负相关[9].目前,国内还少有急性期患者血压与脑出血临床结局关系的大样本研究报道.本研究回顾性分析了1604例急性脑出血患者的临床资料,探讨患者入院时SBP和DBP与住院期间死亡和残疾危险性之间的关系,为急性脑出血患者的血压管理提供参考依据.
English Abstract:
      Multistage sampling techniques are widely applied in the cross-sectional study of epidemiology, while methods based on independent assumption are still used to analyze such complex survey data. This paper aims to introduce the application of weighted estimation methods for the complex survey data. A brief overview of basic theory is described, and then a practical analysis is illustrated to apply to the weighted estimation algorithm in a stratified two-stage clustered sampling data. For multistage sampling survey data, weighted estimation method can be used to obtain unbiased point estimation and more reasonable variance estimation, and so make proper statistical inference by correcting the clustering, stratification and unequal probability effects.
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