| 谭晓华,郭淑霞,张景玉,狄春红,杨磊,曹亦菲,何平,王菊萍,魏兴武.HIV-1辅助受体及配体基因多态性在新疆高危人群中的分布[J].Chinese journal of Epidemiology,2011,32(2):201-203 |
| HIV-1辅助受体及配体基因多态性在新疆高危人群中的分布 |
| Distribution of gene variants regarding co-receptor and their figands among HIV-I infected and uninfected high-risk groups in Xinjiang Uighurs Autonomous Region,China |
| Received:May 26, 2010 |
| DOI： |
| KeyWord: 维吾尔族 艾滋病毒 |
| English Key Word: Uighurs Human immunodeficiency virus |
| FundProject:国家自然科学基金(30700687)；新疆生产建设兵团医药卫生专项课题(05GG36) |
| Author Name | Affiliation | E-mail | | TAN Xiao-hua | School of Medical and Health Administration, Hangzhou Normal University, Hangzhou 310036, China | | | GUO Shu-xia | Shihezi University School of Medicine | | | ZHANG Jing-yu | Shihezi University School of Medicine | | | DI Chun-hong | School of Medical and Health Administration, Hangzhou Normal University, Hangzhou 310036, China | | | YANG Lei | School of Medical and Health Administration, Hangzhou Normal University, Hangzhou 310036, China | yanglei62@yahoo.com | | CAO Yi-fei | School of Medical and Health Administration, Hangzhou Normal University, Hangzhou 310036, China | | | HE-ping | School of Medical and Health Administration, Hangzhou Normal University, Hangzhou 310036, China | | | WANG Ju-ping | Yining Center for Diseases Control and Prevention, Xinjiang Uygur Autonomous Region | | | WEI Xing-wu | Institute of Health Inspection of Shihezi | |
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| Abstract: |
| CD4分子和一些辅助受体是Hiv-l识别、黏附并入侵宿主细胞所必需的。CCR5和CXCR4是Hiv-1最主要的2个辅助受体，此外一些HIV还可利用CCR2等作为辅助受体。研究发现，这些辅助受体及其配体的某些基因多态性与Hlv-1易感和/或疾病进展相关 |
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