Abstract
嵇红,祁贤,李亮,祖荣强,许可,霍翔,吴斌,秦圆方,付建光,汤奋扬,朱凤才,汪华.江苏省甲型H1N1流感裂解疫苗的免疫效果分析[J].Chinese journal of Epidemiology,2011,32(3):321-322
江苏省甲型H1N1流感裂解疫苗的免疫效果分析
Analysis on the immune effect of influenza A(H1N1)split—virus vaccine
Received:September 26, 2010  
DOI:
KeyWord: 甲型H1N1流感  抗体反应
English Key Word: InfluenzaA(HINl)  Antibody response
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Author NameAffiliationE-mail
JI Hong Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009. China  
QI Xian Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009. China  
LI Liang Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009. China  
ZU Rongqiang Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009. China  
XU Ke Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009. China  
HUO Xiang Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009. China  
WU Bin Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009. China  
QIN Yuanfang Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009. China  
FU Jianguang Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009. China  
TANG Fenyang Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009. China  
ZHU Fengcai Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009. China  
WANG Hua Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009. China hua@jscdc.Cn 
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Abstract:
      2009年甲型H1N1流感的流行引起了广泛重视,接种疫苗是预防流感流行、降低死亡率和病死率的最有效方法[1],本研究通过比较不同人群甲型H1N1抗体水平变化趋势,初步评估甲型H1N1流感裂解疫苗的免疫效果. 1.对象与方法: (1)研究对象:2009年11月、12月、2010年2月,在江苏省随机选择甲型H1N1流感疫苗接种人群(免疫人群),连续采集同一批人群(共281人)免疫前、免疫后1个月及3个月的血清标本(排除季节性流感疫苗接种者和接种前1个月内有流感样症状者);连续采集甲型H1N1流感确诊病例(发病时间为2009年10月15日至11月15日,经RT-PCR检测确诊为甲型H1N1流感病毒感染[1])同一组病例发病2周内(107例)、发病后1个月(77例)及3个月(52例)的血清标本(排除甲型H1N1流感疫苗和季节性流感疫苗接种者),选择同时期自然人群作为背景资料.
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