低钠富钾替代盐对农村社区人群血压影响的现场观察

张高辉; 马吉祥; 郭晓雷; 董静; 陈希; 张吉玉; 苏军英; 唐俊利; 徐爱强

Abstract

张高辉,马吉祥,郭晓雷,董静,陈希,张吉玉,苏军英,唐俊利,徐爱强.低钠富钾替代盐对农村社区人群血压影响的现场观察[J].Chinese journal of Epidemiology,2011,32(9):859-863

低钠富钾替代盐对农村社区人群血压影响的现场观察

Field observation on the effect of Iow-sodium and high-potassium salt substitute on blood pressure in ruralcommunity-based population in China

Received:March 31, 2011

DOI：

KeyWord: 高血压低钠富钾替代盐社区人群干预效果

English Key Word: pertension Low-sodium and high-potassium salt substitute Community population Intervention effect

FundProject:卢森堡-世界卫生组织-山东省农村卫生人员培训及慢病控制项目(2007--2010)

Author Name	Affiliation	E-mail
ZHANG Gao-hui	Institute of Eidemiology and Health Statistics, School of Public Health, Shandong University, Jinan 250012, China
MA Ji-xiang	Shandong Provincial Center for Disease Conrol and Prevention
GUO Xiao-lei	Shandong Provincial Center for Disease Conrol and Prevention
DONG Jing	Shandong Provincial Center for Disease Conrol and Prevention
CHEN Xi	Institute of Eidemiology and Health Statistics, School of Public Health, Shandong University, Jinan 250012, China
ZHANG Ji-yu	Shandong Provincial Center for Disease Conrol and Prevention
SU Jun-ying	Shandong Provincial Center for Disease Conrol and Prevention
TANG Jun-li	Shandong Provincial Center for Disease Conrol and Prevention
XU Ai-qiang	Institute of Eidemiology and Health Statistics, School of Public Health, Shandong University, Jinan 250012, China Shandong Provincial Center for Disease Conrol and Prevention	aqxucpi@163.com

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Abstract:

目的评价市售低钠富钾替代盐对农村社区居民血压的影响效果。方法采用流行病学类实验设计，在山东省莱芜市2个农村社区。经过血压筛查，将411名30-60岁的研究对象分为高血压组和非高血压组，两组均以家庭为单位给予3个月的低钠富钾替代盐替换普通食盐进行干预.定期观察血压及其24 h尿钠的变化。结果用低钠富钾替代盐干预1个月时高血压组和非高血压组人群血压开始呈下降趋势，3个月后评估时高血压组收缩压(SBP)平均下降7.4 mmHg(1mmHg=0.133kPa；t=10.096。P=0.000)，舒张压(DBP)下降3.8mmHg(t=8.017，P=0.000)；非高血压组SBP平均下降1.2 mmHg(t=2.507。P=0.007).DBP下降1.0mmHg(t=2.987，P=0.002)。干预3个月后评估时高血压组24 h尿钠平均下降15.5 mmol(t=1.803。p=0.037).尿钾上升4.2mmol(t’=2.132，P=0.018)，钠钾比下降1.2(t----2.786，P=0.003)；非高血压组24 h尿钠平均下降1.7retool(t=0.211。P=0.417)，尿钾上升3.7mmol(t’=2.207，P=0.015)，钠钾比值下降O.7(‘=1.818。P=O.036)。结论低钠富钾替代盐能有效降低人群血压水平，且人群依从性较好，是-种有效的非药物预防控制高血压方法。

English Abstract:

Objective To investigatet he effect of commercial low-sodium and high- potassium salt substitutes on blood pressure in the rural community-based population in China.Methods We conducted a quasi-experiment on 4ll adults,who were 30 to 60 years of age.in 2 rural communities from Laiwu city in Shandong province of China on data from blood pressure screening.The subjects were divided into 2 groups：high blood pressure(HBP)and non-HBP(NHBP).Both groups and their family members took a low-sodium and high.potassium salt substitute for 3 months to replace the normal salt in their bodies.Blood pressure(BP)and 24一hour urinary sodium and potassium were measured regularly in the 2 groups.Resuits There was a continuously decreasing trend for BP at the end of the first month.me months lateT.the mean BP decreased by 7.4 mmHg(1 mmHg=0.133kPa。t=10.096.P=O.000)for SBP and 3.8 mmHg(I=8.017,P=O.000)for DBP in the HBP group.when compared to a 1.2 mm Hg(t=2.507。P=0.007)decrease on SBP and 1.0 mmHg(t=2.987，P=0.002)on DBP in the NHBP group.The mean urinarys odium had a decrease of 15.5 retool／24 h(t=1.803.P=0.037).but the urinary potassium increased by 4.2retool／ 24h(t’=2.132.P=0.018).The result of urinary sodium appepared to be as foIiows：potassium ratio (Na+／K+)decreased by 1.2(t---=-2.786.P----0.003)in the HBP group.HowevJat‘.in NHBP group.the mean urinary sodium decreased by 1.7 mm01／24 h(I=O.2ll。P--0.417)and urinary potassium increased by 3.7 mmol/24h(t’=2.207，P=O.015)，together with the decrease ofNa⁺／K⁺by O.7(f=1.818,P=0.036).Conclnsion Results from our stuay clearlyd emonstrated that the intake of low.sodium and high-potassium salts ubstitute could effectively reduce the BP with good compliance among adults in the rural community-based population in China.This was all effective but non-medical method to prevent and control the high blood pressure.

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