早产儿和足月儿乙型肝炎疫苗初次免疫和再次免疫抗体应答配对分析

刘甲野; 颜丙玉; 张丽; 徐爱强; 吕静静; 冯艺; 龚晓红; 崔富强; 梁晓峰; 李波; 陈德颖; 吉秀兰; 陈士玉

Abstract

刘甲野,颜丙玉,张丽,徐爱强,吕静静,冯艺,龚晓红,崔富强,梁晓峰,李波,陈德颖,吉秀兰,陈士玉.早产儿和足月儿乙型肝炎疫苗初次免疫和再次免疫抗体应答配对分析[J].Chinese journal of Epidemiology,2011,32(10):1055-1056

早产儿和足月儿乙型肝炎疫苗初次免疫和再次免疫抗体应答配对分析

Matching study on antibody response between preterm and full-term infants after primary immunization and revaccination of hepatitis B

Received:March 07, 2011

DOI：10.3760/cma.j.issn.0254-6450.2011.10.025

KeyWord: 早产儿乙型肝炎疫苗抗体应答

English Key Word: Preterm infants Hepatitis B vaccine Antibody response

FundProject:国家科技重大专项(2008ZX 10002-001，2009ZX 10002- 028)

Author Name	Affiliation	E-mail
LIU Jia-ye	Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Shandong Provincial Center for Disease Control and Prevention, Jinan 250014, China
YAN Bing-yu	Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Shandong Provincial Center for Disease Control and Prevention, Jinan 250014, China
ZHANG Li	Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Shandong Provincial Center for Disease Control and Prevention, Jinan 250014, China	zl9127@163.com
XU Ai-qiang	Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Shandong Provincial Center for Disease Control and Prevention, Jinan 250014, China
LV Jing-jing	Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Shandong Provincial Center for Disease Control and Prevention, Jinan 250014, China
FENG Yi	Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Shandong Provincial Center for Disease Control and Prevention, Jinan 250014, China
GONG Xiao-hong	Chinese Center for Disease Control and Prevention
CUI Fu-qiang	Chinese Center for Disease Control and Prevention
LIANG Xiao-feng	Chinese Center for Disease Control and Prevention
LI Bo	Yantai Center for Disease Control and Prevention
CHEN De-ying	Weihai Center for Disease Control and Prevention
JI Xiu-lan	Shouguang Center for Disease Control and Prevention
CHEN Shi-yu	Zhangqiu Center for Disease Control and Prevention

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Abstract:

早产儿作为一类特殊群体，其T、B细胞功能发育未成熟的问题比较突出[1]。早产儿乙型肝炎（乙肝）疫苗（HepB）免疫效果一直以来备受关注，虽然国内外已开展一些相关研究[2,3]，但仍存在很大争议。本研究通过配对研究方法，对早产儿和足月儿HepB初次免疫和低、无应答者再次免疫后的抗体应答进行观察。

English Abstract:

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