| 韦所苏,邹云锋,吴腾燕,蒋俊俊,林新勤,黎明强,吴德仁,徐娜,韦富梅,谢培彦,钟晓妮,梁浩,黄爱龙.广西女性性工作者暴露前药物预防HIV感染接受意愿及其影响因素研究[J].Chinese journal of Epidemiology,2011,32(11):1091-1094 |
| 广西女性性工作者暴露前药物预防HIV感染接受意愿及其影响因素研究 |
| Acceptability and influencing factors on pre-exposure prophylaxis programs among female sex workers in Guangxi,China |
| Received:May 28, 2011 Revised:June 07, 2012 |
| DOI： |
| KeyWord: 艾滋病病毒 女性工作者 暴露前药物预防 接受意愿 |
| English Key Word: Human immunodeficiency virus Female sex workers Pre-exposure prophylaxis Acceptabilit |
| FundProject:国家“十一五 ”科技重大专项(2008ZX10001-016);广西高教人才小高地建设创新团队资助计划（桂教人[2010]38号）；广西“新世纪十百千人才工程”人选课题（桂人社办发[2010] 31 |
| Author Name | Affiliation | E-mail | | WEI Suo-su | School of Public Health,Guangxi Medical University | haolphd@163.com;ahuang1964@yahoo.com.cn | | ZOU Yun-feng | School of Public Health,Guangxi Medical University | | | WU Teng-yan | School of Public Health,Guangxi Medical University | | | JIANG Jun-jun | School of Public Health,Guangxi Medical University | | | LIN Xin-qin | Guangxi Key Laboratory Cultivation Base of AIDS Prevention and Treatment, Nanning 530021,China | | | LI Ming-qiang | Nanning City Center for Disease Control and Prevention | | | WU De-ren | Liuzhou City Center for Disease Control and Prevention | | | XU Na | School of Public Health,Guangxi Medical University | | | WEI Fu-mei | School of Public Health,Guangxi Medical University | | | XIE Pei-yan | School of Public Health,Guangxi Medical University | | | ZHONG Xiao-ni | Chongqing Medical University | | | LIANG Hao | School of Public Health,Guangxi Medical University | | | HUANG Ai-long | Chongqing Medical University | |
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| Abstract: |
| 目的 了解广西地区南宁、柳州、北海市女性性工作者(FSWs)对暴露前药物预防(PrEP)HIV感染的接受意愿及其影响因素。方法 采用横断面设计，方便抽样的方法选取3市405名FSWs进 行问卷调查，了解FSWs的AIDS相关危险行为、对PrEP的知晓情况及其接受意愿。结果 在了解PrEP后，对于“如果PrEP预防HIV感染安全、有效且免费提供”，405人中有85.9%表示愿意接受。logistic回归分析显示，与PrEP接受意愿有关的因素为：工作场所(OR=2.256，P=0.009)、月经济收入(OR=0.257，P=0.004)、与家人的关系(OR=0.338，P=0.012)、AIDS知晓情况（OR=2.802，P=0.028）、认为HIV感染危险来自陌生性伴（OR=0.363，P= 0.049）、老板是否规定使用安全套（OR=0.432，P=0.01 0）、商业性行为时是否全程使用安全套(OR=3.010，P=0.002)、是否使用过药物预防性病（OR＝3.570，P=0.049）。结论 对HIV/AIDS相关知识的知晓程度及自我保护意识的高低可能是影响FSWs接受PrEP的主要因素。以健康教育的形式宣传PrEP是提高其接受意愿的较好方式。 |
| English Abstract: |
| Objective To study the acceptability of pre-exposure prophylaxis (PrEP)program on prevention of human immunodeficiency virus (HIV)infection among female sex workers (FSWs) in Guangxi of China.Methods A cross-sectional survey using convenience sampling was administered among 405 FSWs in Nanning,Liuzhou and Beihai cities of Guangxi,China.Self-designed questionnaire,face to face interviews were used to collect HIV-related risk behaviors,knowledge and acceptability of PrEP.Results After an introduction on PrEP,presuming that it was effective,safe and free of charge,85.9% of the 405 FSWs said they would use it.Data from logistic regression analysis showed that significant factors of intent to use PrEP would include the followings:workplace (OR=2.256,P=0.009), monthly income (OR=0.257,P=0.004),family closeness (OR＝0.338,P＝0.012),knowledge onHIV/AIDS (OR＝2.802,P=0.028),HIV/AIDS riskwas introduced fromastrange client (OR＝0.363, P＝0.049),whether thegatekeeper ordering theuseof condom (OR＝0.432,P=0.010),whether consistent using condom with clients (OR＝3.010,P＝0.002),whether ever using drugs to prevent STD infection (OR=3.570,P=0.049) etc. Conclusion Awareness on HIV/AIDS knowledge and self-protection seemed the main influential factors while health education might promote the acceptability of PrEP. |
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