辽宁省大棚作业农民慢性阻塞性肺疾病危险因素分析

刘朔; 李丽云; 李振华; 闻德亮; 王笑歌

Abstract

刘朔,李丽云,李振华,闻德亮,王笑歌.辽宁省大棚作业农民慢性阻塞性肺疾病危险因素分析[J].Chinese journal of Epidemiology,2012,33(3):280-285

辽宁省大棚作业农民慢性阻塞性肺疾病危险因素分析

Risk factors on chronic obstructive pulmonary disease among greenhouse workers in Liaoning province

Received:October 24, 2011

DOI：

KeyWord: 慢性阻塞性肺疾病危险因素大棚作业

English Key Word: Chronic obstructive pulmonary disease Risk factors Greenhouse workers

FundProject:”十一五”国家科技支撑计划(2007BAI24B04);中华医学会基金(07010320040,08020680146);辽宁省教育厅基金(2009A760)

Author Name	Affiliation	E-mail
LIU Shuo	Department of Respiratory Diseases, the Fourth Affiliated Hospital of China Medical University, Shenyang 110032, China
LI Li-yun	Department of Infectious Diseases, the Fourth Affiliated Hospital of China Medical University, Shenyang 110032, China
LI Zhen-hua	Department of Respiratory Diseases, the First Affiliated Hospital of China Medical University
WEN De-liang	China Medical University, the First Affiliated Hospital of China Medical University	cmu_vip@126.com
WANG Xiao-ge	Department of Respiratory Diseases, the Fourth Affiliated Hospital of China Medical University, Shenyang 110032, China	cm4hwxgn2005@126.com

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Abstract:

目的探讨大棚作业人群慢性阻塞性肺疾病(COPD)患病危险因素.方法 2006-2009年采用随机、分层、整群抽样方法,对辽宁省800余个大棚从事作业的农民进行统一问卷调查、体格(血常规、血气分析、胸部X线及肺功能)检查,COPD确诊按照中华医学会呼吸病学分会制定的《慢性阻塞性肺疾病诊治指南》(2007年修订版)诊断标准.结果共调查从业人员5880人,有效应答者5420人,有效应答率92.18％.年龄(x²＝32.530,P=0.000)、棚内日劳作时间(x²=21.311,P=0.000)、大棚通风频率(x²=9.79l,P=0.007)及大棚面积(x²=73.645,P=0.000)危险因素存在地区差异.logistic回归分析提示,吸烟(OR=1.976,95％CI:1.672～2.334)、年龄(OR=4.188,95％CI:3.718 ～ 4.718)、菌棚(相对于蔬菜棚,OR=1.302,95％CI:1.016 ～ 1.669)、花卉棚(相对于蔬菜棚,OR=1.503,95％CI:1.201～1.880)为大棚作业农民COPD的危险因素；从业年限(OR=0.684,95％CI:0.609 ～ 0.767)是大棚作业农民COPD的保护因素.结论辽宁省大棚作业农民COPD的发生与多种因素相关,应重视其防治.

English Abstract:

Objective To study the risk factors of chronic obstructive pulmonary disease (COPD) among greenhouse farmers in Liaoning province.Methods According to geographical differences in Liaoning province,stratified-cluster-random sampling method was used.A total of 5420 greenhouse farmers working in more than 800 greenhouses were investigated with unified questionnaire,physical examination,blood routine examination,blood gas analysis,chest X-ray and pulmonary function tests.Diagnosis of COPD was made according to the criteria for "chronic obstructive pulmonary disease of diagnosis and treatment guidelines" (2007 revision) by the Chinese Respiratory Disease Society.Results The total number of farmers under study was 5880,including 5420 respondants(92.18％) with effective data.Risk factors were found on age(x²＝32.530,P=0.000),time working in greenhouses every day ( x²=21.311,P =0.000 ),frequency of ventilation ( x²=9.791,P=0.007) and the location of the greenhouses(x²=73.645,P=0.000).When using SPSS 17.0 for the single factor logistic regression analysis,results indicated that smoking(OR＝1.976,95％CI:1.672-2.334),age ( OR =4.188,95 ％ CI:3.718-4.718 ),greenhouses for fungus ( compared with vegetables,OR=1.302,95％CI:1.016-1.669),flowers and plants (compared with vegetables greenhouses,OR=1.503,95％ CI:1.201-1.880) were the risk factors of COPD among greenhouse farmers while the protective factor was the years of working in the greenhouse (OR=0.684,95％ CI:0.609-0.767).Conclusion The overall morbidity of COPD among greenhouse farmers in Liaoning province was 17.47％ with various risk factors.

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