Abstract
李敏,时景璞.疗效比较研究的方法学应用及其实施过程[J].Chinese journal of Epidemiology,2012,33(11):1185-1188
疗效比较研究的方法学应用及其实施过程
The process of application and implementation on methodologies for comparative effectiveness research
Received:May 30, 2012  
DOI:10.3760/cma.j.issn.0254-6450.2012.11.020
KeyWord: 疗效比较研究  研究设计  生物统计学
English Key Word: Comparative effectiveness research  Research design  Biostatistics
FundProject:
Author NameAffiliationE-mail
LI Min 1. Department of Clinical Epidemiology, The First Affiliated Hospital

2. Cardiovascular Institute of China Medical University
, Shenyang 110001, China

3. Evidence Based Center of Liaoning Province
 
 
SHI Jing-pu 1. Department of Clinical Epidemiology, The First Affiliated Hospital

2. Cardiovascular Institute of China Medical University
, Shenyang 110001, China

3. Evidence Based Center of Liaoning Province
 
sjp56@yahoo.Com 
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Abstract:
      疗效比较研究(CER)可有效比较诊疗措施的临床效果,为医疗决策提供证据.其设计除采用大规模临床随机对照试验、整群随机对照试验、类试验、数学模型外,以电子病历为基础的观察性研究备受重视.对研究课题的证据生成、综合、传播及应用的每一环节上,采用CER均需相应的统计学方法进行统计分析和质量控制.
English Abstract:
      Comparative effectiveness research is able to compare the clinical effects of diagnosis and treatment measures effectively, thus providing evidence for making medical decision. In addition that the large-scale clinical randomized controlled trials, cluster randomized trials, quasi-trial, and mathematical models have started to be used in the designing processes of comparative effectiveness research, observational studies on the foundation of electronic medical records have also been paid enough attention. For each research topic, every procedure on the following areas as:generation of a specific piece of evidence, as well as synthesis, communication, translation and application of related data need to have corresponding statistical Methods to perform statistical analysis and quality control.
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