李庆祥,张莹,王梅,朱小玲.冠心病患者动脉粥样硬化性颈动脉狭窄筛查及危险因素分析[J].Chinese journal of Epidemiology,2013,34(6):626-629 |
冠心病患者动脉粥样硬化性颈动脉狭窄筛查及危险因素分析 |
Study on the screening program and risk factors of carotid artery stenosis with coronary artery disease |
Received:December 20, 2012 Revised:June 28, 2012 |
DOI: |
KeyWord: 冠心病 颈动脉狭窄 危险因素 |
English Key Word: Coronary artery disease Carotid artery stenosis Risk factor |
FundProject:首都发展基金 |
Author Name | Affiliation | E-mail | LI Qing-xiang | The 35thWards,Anzhen University and Beijing Institute of Heart, Lung and Blood Cardiovascular Department,Beijing Xuanwu TCM Hospital Diseases Beijing 100029,China | aelqx@126.com | ZHANG Ying | Cardiovascular Department,Beijing Xuanwu Hospital | | WANG Mei | The 35thWards,Anzhen University and Beijing Institute of Heart, Lung and Blood Cardiovascular Department,Beijing Xuanwu TCM Hospital Diseases Beijing 100029,China | | ZHU Xiao-ling | The 35thWards,Anzhen University and Beijing Institute of Heart, Lung and Blood Cardiovascular Department,Beijing Xuanwu TCM Hospital Diseases Beijing 100029,China | |
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Abstract: |
目的分析冠心病患者伴动脉粥样硬化性颈动脉狭窄(CAS)的临床特点及其危险因素.方法1339例经冠脉造影诊断为冠心病的患者住院期间行颈动脉超声检查.结果CAS发生率为11.8%(158/1339).CAS组年龄、既往患脑卒中的比率高于非CAS组,差异有统计学意义(P<0.01,P=0.02).CAS的发生率随冠脉病变程度加重而增加(x2=37.482,P<0.01).冠脉左主干病变的患者其CAS发生率明显高于其他病变(x2=38.93,P<0.01).多因素logistic回归分析,只有年龄、脑卒中史、冠脉左主干病变和多支病变是CAS的独立危险因素.结论冠心病患者伴发CAS与冠脉病变严重程度相关,年龄增加和脑卒中病史是CAS发生的独立危险因素. |
English Abstract: |
Objective The purpose of this research project was to evaluate the relationship and risk factors between coronary artery disease and carotid artery stenosis (CAS),screened by duplex ultra-sonography.Methods 1339 patients with coronary artery disease were enrolled into this study.All patients performed carotid duplex ultra-sonography during hospitalization after coronary artery angiography.Results The overall incidence of CAS was 11.8% (158/1339).Patients under older age and having history of stroke,the incidence rates were higher than other groups (P< 0.01,P =0.02).The incidence of CAS in patients with multi-vessel lesions was higher than those of diseases involved in one vessel (x2=37.482,P<0.01).CAS patients having left side major diseases,the incidence was higher than those of others (x2=38.93,P<0.01).By multivariable logistic regression analysis,factors as:older age,having had history of stroke,with left side major disease and multivessel lesions etc.appeared to be independent predictors of CAS,respectively.Conclusion Patients with coronary artery diseases had higher prevalence rates for CAS when suffering from multi-vessel lesions or stenosis of left major stem.Factors as being elderly,having history of cerebro-vascular diseases were independent predictors of CAS in patients with coronary artery diseases. |
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