河南省2010-2012年艾滋病暴露婴幼儿营养不良影响因素分析

王奇; 王哲; 孙定勇; 马楠; 李宁; 马彦民

Abstract

王奇,王哲,孙定勇,马楠,李宁,马彦民.河南省2010-2012年艾滋病暴露婴幼儿营养不良影响因素分析[J].Chinese journal of Epidemiology,2013,34(11):1083-1085

河南省2010-2012年艾滋病暴露婴幼儿营养不良影响因素分析

Risk factors associated with malnutrition of infants exposed to HIV in Henan province。2010-2012

Received:June 05, 2013

DOI：10.3760/cma.j.issn.0254-6450.2013.011.009

KeyWord: 艾滋病毒营养不良婴幼儿

English Key Word: Human immunodeficiency virus Malnutrition Infant

FundProject:“十二五”国家科技重大专项(2012zxl0004—905)

Author Name	Affiliation	E-mail
WANG Qi	Institute of STD and AlDS Prevention and Control.Henan Prouicinal Center for Disease Control and Prevention.Zhengzhou 450016.China
WANG Zhe	Institute of STD and AlDS Prevention and Control.Henan Prouicinal Center for Disease Control and Prevention.Zhengzhou 450016.China	wangzhe@hncdc.com.cn
SUN Ding-gong	Institute of STD and AlDS Prevention and Control.Henan Prouicinal Center for Disease Control and Prevention.Zhengzhou 450016.China
MA Nan	Henan Provicinal Academy of Medical Sciences
LI Ning	Institute of STD and AlDS Prevention and Control.Henan Prouicinal Center for Disease Control and Prevention.Zhengzhou 450016.China
MA Yan-min	Institute of STD and AlDS Prevention and Control.Henan Prouicinal Center for Disease Control and Prevention.Zhengzhou 450016.China

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Abstract:

目的了解河南省农村地区艾滋病暴露婴幼儿18月龄前营养不良情况，分析其影响因素。方法对河南省农村地区2010--2012年艾滋病产妇分娩的婴幼儿分别在1、3、6、9、12、18月龄时，记录身高、体重，计算年龄别体重、年龄别身高、身高别体重z值评分并进行营养评估，收集孕产妇免疫指标、婴幼儿HIV检测结果，采用logistic回归分析影响因素。结果随访至18月龄婴幼儿157名，其中HIV阳性32名、阴性125名，不同月龄HIV阴性婴幼儿消瘦、低体重、生长发育迟缓发生率最高分别为8.8%、16.8%、30.4%；不同月龄HIV阳性婴幼儿消瘦、低体重、生长发育迟缓发生率最高分别为15.0%、30.0%、41.7%。孕妇孕期贫血(艘=2.05，95%CI：1.15～3.66)、孕期CD4+T淋巴细胞计数低(RR=1.43，95%CI：1.18。1.74)、婴幼儿添加辅食早于4月龄(RR=1.96，95%CI：1.40.2.74)是婴幼儿营养不良的危险因素；婴幼JLH眨.用抗病毒药物(RR=0.14，95%CI：o.02。1.04)、婴幼儿出生体重正常(RR=0.08，95%CI：0.04～0.15)是婴幼儿营养不良的保护因素。结论艾滋病暴露婴幼儿18月龄前营养不良发生率处于较高水平，应加强孕期保健和人工喂养指导及婴幼儿生长发育监测工作，预防婴幼儿营养不良发生。

English Abstract:

Objective To examine the malnutrition status of infants exposed to HIV in ruralareas of Henan province and related risk factors.Methods Z scores of weight for age,height for ageand weight for height of infants exposed to HIV in rural areas of Henan province born in 2010-2012were calculated at 1,3,6.9,1 2 and l 8 months of age.Z scores were used to evaluate the nutritionstatus of infants under study.Data regarding the pregnant women and infants were collected andanalyzed by non-conditionallogistic regression model.Resuits One hundred fifty.seven infants weresurveyed in which l 25 were HIV negative and 32 were HIV positive.The incidence rates ofunderweight.athrepsia and growth retardation of HIV-negative infants were 8.8%,1 6.8%and 30.4%。respectively.The incidence rates of underweight,athrepsia and growth retardation among theHIV-positive infants were 15.0%,30.O%and 41.7%％,respectively.Anemia in pregnancy(RR=2.05,95%C1.15-3.66),lOW count ofCD₄⁺T leukomonocyte(RR=1.43,95%C1.18-1.74),status ofcomplementary feeding before 4 months old(RR=1.96,95%CI：1.40-2.74)might serve as the riskfactors related to the situation.Inrants received antiviral treatment(RR=0.14.95%CI：0.02-1.04).normal birth weight(RR=0.08.95%CI：0.04-0.15)might serve as the protective factors.Conclusion The malnutrition incidence was high among those infants younger than l 8 months exposed to HIV inrural area of Henan province.Essential health services such as antenatal care.artificial feeding andgrowth monitoring for infants and pregnant infants should be provided to prevent malnutrition amongthese sub-populations.

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