| 刘军延,赵小元,程红,侯冬青,米杰.北京市学龄儿童肥胖类型与心血管危险因素的关联性研究[J].Chinese journal of Epidemiology,2014,35(1):3-8 |
| 北京市学龄儿童肥胖类型与心血管危险因素的关联性研究 |
| Association between different types of obesity and cardiovascular risk factors in school-aged children |
| Received:July 16, 2013 |
| DOI： |
| KeyWord: 肥胖 中心性肥胖 心血管危险因素 学龄儿童 |
| English Key Word: Obesity Abdominal obesity Cardiovascular risk factor School-aged children |
| FundProject:国家自然科学基金(81172746)；北京市科技计划重点项目(H030930030130，D11110700060000) |
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| Abstract: |
| 目的分析学龄儿童肥胖类型与心血管危险因素间的关联。方法选择“北京市儿童青少年代谢综合征研究(BCAMS)”中3508名(2 054名非肥胖、1 454名肥胖)6～18岁儿童青少年作为研究对象。采用问卷调查收集人口学资料，并测量身高、体重、腰嗣和血压，检测空腹血糖和血脂。研究对象划分为非肥胖、一般性肥胖、中心性肥胖和复合型肥胖4种类型，并根据血脂异常、空腹血糖受损(IFG)和高血压进行心血管危险因素聚集分析。采用多元线性回归以及多因素logistic回归，分析儿童肥胖类型与心血管危险因素之间的关联。结果血压、血糖和血脂(TC除外)水平及血脂异常与高血压患病率均随非肥胖、一般性肥胖、中心性肥胖至复合型肥胖逐渐升高(P<0.001)；各不同类型肥胖组间IFG率的差异无统计学意义。控制年龄、性别、青春发育期后，中心性肥胖和复合型肥胖组发生一种心血管危险因素的风险分别为非肥胖组的1.54倍和2.51倍；而一般性肥胖组与非肥胖组相比，发生一种心血管危险因素风险的差异无统计学意义；一般性肥胖、中心性肥胖和复合型肥胖组发生两种及以上心血管危险因素的风险分别是非肥胖组的3.32、2.2l和7.42倍，发生3种及以上心血管危险因素的风险分别是非肥胖组的3.10、3.67和10.75倍。随着肥胖类型的变化，心血管危险因素的聚集性有逐渐升高趋势(|P结论北京市儿童青少年心血管危险因素水平及聚集风险随肥胖类型的变化而升高，其中复合型肥胖最高，其他依次为中心性肥胖和一般性肥胖。 |
| English Abstract: |
| 0bjective The aim of this P印er was to analyze the association between different types of obesity and cardiovascular risk factors(CRFs)in school—aged children.Methods 3508 children aged 6一l 8 years old including 2 054 non.obese and 1 454 obese children were chosen as the population under study，from Beijing Children and Adolescents Metabolic Syndrome Study.Demographic data was collected through questionnaires while height，weight，waist circumference，and blood pressure were measured through physical check—up.Fasting blood glucose and blood lipids were also tested.Children were divided into four groups：without obesity，with general obesity，with abdominal obesity and with combined obesity.CRFs including dyslipidemia.impaired fasting glucose(IFG).and hypertension were scored.Multiple linear regression and logistic regression analyses were performed to assess the association between different types of obesity and CRFs.Results From non-obese children.children under general.obesity，abdominal obesity and those with combined types of obesity.there appeared an increasing fiend in the levels of blood pressure，blood glucose，and blood lipids.the prevalence dyslipidemia and hypertension(P<0.001).There were no significant differences in the risks of IFG among four types of obesity.After controlling for age，sex，and puberty stage.when compared with non.obese children，those children with abdominal obesity or combined types of obesity had 1.54 and 2.5 1 times of risks to only one CRF，while generally obese children had similar risk of dyslipidemia.When compared to the non—obese ones.children with general obesity. abdominal obesity，or combined types of obesity showed 3.32.2.21 and 7.42 times of risks to≥2 CRFs and 3.10.3.67 and 10.75 times of risks to≥3 CRFs.The cluster of CRFs increased with the levels of obesity(P<0.001).Conclusion Levels and cluster of CRFs were increasing along with the levels of obesity in sch001.aged children in Beiiing.Children with combined types of obesity had the highest risk of clustering CRFs.followed by those with abdominal obesity and general obesity. |
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