刘秀荣,周艳茹,王建军,刘星,杨春伟,李俊娟,陈朔华,吴寿岭.中心性肥胖对2型糖尿病新发脑梗死事件的影响[J].Chinese journal of Epidemiology,2014,35(4):390-392 |
中心性肥胖对2型糖尿病新发脑梗死事件的影响 |
Effect of central obesity Oil the events of new.onset cerebral infarction among type 2 diabetes mellitus patients |
Received:September 24, 2013 |
DOI:10.3760/cma.j.issn.0254-6450.2014.04.010 |
KeyWord: 糖尿病,2型 中心性肥胖 脑梗死 风险 |
English Key Word: Diabetes mellirus,type 2 Central obesity Cerebral infarction Risk |
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Abstract: |
目的 探讨中心性肥胖对2型糖尿病新发脑梗死事件的影响。方法 采用前瞻性队列研究方法 ,在2006--2007、2010--2011年开滦集团健康体检在职及离退休职工中,选择符合人选标准的8306名2型糖尿病患者作为研究队列,依据基线WC水平分为中心性肥胖组和非肥胖组,应用多变量Cox比例风险凹归模型分析中心性肥胖对2型糖尿病新发脑梗死事件的影响。平均随访38~53(48.05±3.09)个月。结果 (1)中心性肥胖组人群的平均年龄、BMI、SBP、DBP、脉压、FPG、TC、TG、LDL.C、UA水平均高于非肥胖组(P结论 中心性肥胖增加2型糖尿病新发脑梗死事件的风险。 |
English Abstract: |
Objective To analyze the effect of central obesity on new-onset cerebralinfarction events among type 2 diabetes mellitus patients in the Kailuan Group.Methods This was aprospective cohort study.In a total of 101 510 employees who had been camed out a healthyexamination in Kailuan Group from Jul.2006 to Oct.2007.8 306 type 2 diabetes mellitus patientswere selected.According to the baseline waist measurement.the observed population was divided into two groups--with central obesity or without.The total period of follow.u口was 38-53(48.05±3.09)months.Results 1)Mean age,BMI。the levels of SBP,DBP,pulse pressure,FPG,TC.LDL.C,uricacid significant increased in the central obesity group were higher than in the non.obese group(P<0.01).2)The incidence of new onset cerebral infarction in obese group was higher than that in thenon.obese group(3.1%vs.1.6%.6.8%.PConclusion Type 2 diabetes mellitus patients with central obesity seemed to have increasedthe risk of new-onsetcerebralinfarction events. |
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