张彩凤,施继红,黄喆,李慧英,魏晓明,林黎明,邢爱君,陈朔华,吴寿岭.理想心血管健康行为和因素对新发高血压的影响[J].Chinese journal of Epidemiology,2014,35(5):494-499 |
理想心血管健康行为和因素对新发高血压的影响 |
Relationship between‘ideal'cardiovascular behaviors and factors and the incidence of hypertension |
Received:October 16, 2013 |
DOI:10.3760/cma.j.issn.0254-6450.2014.05.006 |
KeyWord: 高血压 理想心血管健康行为和因素 前瞻性队列研究 |
English Key Word: Hypertension Ideal cardiovascular behaviors and factors Prospective cohort study |
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Abstract: |
目的 探讨理想心血管健康行为和因素对新发高血压的影响。 方法 采用前瞻性队列研究,以参加2006-2007年度健康查体的开滦集团职工为研究对象,排除既往高血压病、 心肌梗死、 脑梗死以及资料不全者,最终52 133人纳入队列,观察队列人群中高血压发病情况。依据美国心脏协会定义的理想心血管健康行为和因素,采用寿命表法计算高血压累积发病率,利用Cox风险比例回归模型比较不同理想心血管健康行为和因素个数人群间高血压发病风险。结果 具备0~1和5~7项理想心血管健康行为和因素者高血压患病率分别为65.72%、 59.14%、 54.59%、50.24%、 34.22%。校正年龄、 高血压家族史、 文化程度及家庭经济状况等因素后,与具有0~1项心血管健康行为和因素的人群相比,具备2、 3、 4、 5~7项者高血压患病风险分别为0.75、 0.69、 0.63和0.36倍,其中男性人群分别为0.77、 0.76、 0.65和0.45倍,女性人群分别为0.83、 0.50、 0.73和0.36倍。结论 随理想心血管健康行为和因素个数增加,高血压患病率及发病风险降低。 |
English Abstract: |
Objective To explore the relationship between‘ideal'cardiovascular behaviors and factors and the incidence of hypertension. Methods A prospective cohort study including 52 133 workers who had participated in the 2006-2007 Kailuan health examination without history of cerebral infraction, myocardial infarction or hypertension but with complete data, was carried out. All workers were followed on their occurrence of hypertension. According to the AHA definition of‘ideal'cardiovascular health behaviors and factors, the cumulative incidence rates of hypertension in different groups were calculated under the life table method, and compared by Log-rank test, Cox proportional hazards regression was used to calculate the hazard rations and 95% confidence intervals for baseline behaviors and factors. Results The cumulative incidence rates of hypertension according 0-1, 2, 3, 4, 5-7 ideal cardiovascular health behaviors and factors were 65.72%, 59.14%, 54.59%, 50.24% and 34.22%, respectively in the 0-1, 2, 3, 4, 5-7 groups. Data from the Cox proportional hazards model showed that after adjusting for age, education level and family history of hypertension, the ones who had 2, 3, 4, 5-7 ideal cardiovascular behaviors/factors were 0.75, 0.69, 0.63, 0.36 times more than those who had 0-1 ideal behaviors. Conclusion The incidence of hypertension and risk reduced along with the increase of ideal cardiovascular health behaviors and factors. |
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