社区老年糖尿病合并高血压患者对认知功能的影响

高欣; 段春波; 鲍利; 于会艳; 秦斌; 齐若梅; 高芳堃

Abstract

高欣,段春波,鲍利,于会艳,秦斌,齐若梅,高芳堃.社区老年糖尿病合并高血压患者对认知功能的影响[J].Chinese journal of Epidemiology,2014,35(7):784-786

社区老年糖尿病合并高血压患者对认知功能的影响

Effect of type 2 diabetes with hypertension on cognitive function—a study on elderly living in the communities of Beijing

Received:May 07, 2014

DOI：10.3760/cma.j.issn.0254-6450.2014.07.006

KeyWord: 糖尿病, 2 型高血压认知功能老年人

English Key Word: Diabetes mellitus, type 2 Hypertension Cognition Elderly

FundProject:国家自然科学基金（30400361）；北京医院院级课题（BJ-2012-52）

Author Name	Affiliation	E-mail
Gao Xin	Key Laboratory of Geriatrics	gaoxinbj@hotmail.com
Duan Chunbo	Editorial Department of Chinese Journal of Geriatrics
Bao Li	Key Laboratory of Geriatrics
Yu Huiyan	Department of Neurology, Beijing Hospital and Beijing Institute of Geriatrics, Ministry of Health, Beijing 100730, China
Qin Bin	Department of Neurology, Beijing Hospital and Beijing Institute of Geriatrics, Ministry of Health, Beijing 100730, China
Qi Ruomei	Key Laboratory of Geriatrics
Gao Fangkun	Key Laboratory of Geriatrics

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Abstract:

目的了解社区老年糖尿病患者合并高血压对其认知功能的影响。方法选择北京市某社区＞60 岁老年糖尿病患者82 例和糖尿病合并高血压患者142 例为调查对象, 同社区年龄、性别及文化程度相匹配的277 名正常老年人为对照, 以简易智能状态检查量表（MMSE）和蒙特利尔认知评估量表（MoCA）评估三组人群的认知功能状况。结果糖尿病合并高血压患者组较正常对照组MMSE总分降低（28.42±1.52 vs. 28.88±1.47）, 差异有统计学意义（P＜0.05）；糖尿病合并高血压患者组与正常对照组比较, MoCA总得分（25.20±3.91 vs. 26.50±3.29）、视空间与执行功能（3.60±1.56 vs. 3.96±1.18）和语言得分（2.10±0.80 vs. 2.37±0.80）明显降低, 差异有统计学意义（P＜0.05）。多元回归分析显示, 高龄、受教育程度低是认知障碍的独立危险因素（P＜0.01）。结论老年糖尿病患者合并高血压可导致认知功能受损。

English Abstract:

Objective To study the effects of type 2 diabetes（T2DM）with hypertension on cognitive function in those community-based elderly who were aged 60 and over, in Beijing. Methods 82 patients with T2DM, 142 patients with both T2DM and hypertension and 277 normal controls were investigated in this study. Both methods as：the Montreal Cognitive Assessment（MoCA）and Mini-Mental Status Examination（MMSE）were used to determine cognitive change. Results The total MMSE scores showed significant decrease between T2DM with hypertension and controls［（28.42±1.52）vs.（28.88±1.47）, P＜0.05］. The MoCA score of the total scores［（25.20±3.91）vs.（26.50±3.29）, P＜0.05］, sub-scores of visuospatial, executive［（3.60±1.56）vs.（3.96±1.18）, P＜0.05］and language［（2.10±0.80）vs.（2.37±0.80）, P＜0.05］significantly decreased in T2DM patients with hypertension and in the normal controls. Data from the Multiple logistic regression analysis showed that older age and less education were risk factors for cognitive impairment. Conclusion T2DM and hypertension damaged the cognitive function of patients.

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