| 聂珺妍,喻红辉,王智强,汪蕾蕾,韩娟,王友洁,杜玉开,沈敏.儿童期不良经历与成年后慢性病的相关性研究[J].Chinese journal of Epidemiology,2015,36(9):953-957 |
| 儿童期不良经历与成年后慢性病的相关性研究 |
| Association between adverse experiences in childhood and risk of chronic diseases in adulthood |
| Received:January 30, 2015 |
| DOI：10.3760/cma.j.issn.0254-6450.2015.09.010 |
| KeyWord: 儿童期不良经历 慢性病 成年人 相关性 |
| English Key Word: Adverse childhood experiences Chronic disease Adult Relevance |
| FundProject:湖北省自然科学基金(2013CFB125) |
| Author Name | Affiliation | E-mail | | Nie Junyan | Department of Maternal and Child Health, School of Public Health, Huazhong University of Science and Technology, Wuhan 430030, China
1 Department of Maternal and Child Health, School of Public Health, Huazhong University of Science and Technology, Wuhan 430030, China | | | Yu Honghui | Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China1 Department of Maternal and Child Health, School of Public Health, Huazhong University of Science and Technology, Wuhan 430030, China | | | Wang Zhiqiang | Department of Maternal and Child Health, School of Public Health, Huazhong University of Science and Technology, Wuhan 430030, China
1 Department of Maternal and Child Health, School of Public Health, Huazhong University of Science and Technology, Wuhan 430030, China | | | Wang Leilei | Department of Maternal and Child Health, School of Public Health, Huazhong University of Science and Technology, Wuhan 430030, China
1 Department of Maternal and Child Health, School of Public Health, Huazhong University of Science and Technology, Wuhan 430030, China | | | Han Juan | Department of Maternal and Child Health, School of Public Health, Huazhong University of Science and Technology, Wuhan 430030, China
1 Department of Maternal and Child Health, School of Public Health, Huazhong University of Science and Technology, Wuhan 430030, China | | | Wang Youjie | Department of Maternal and Child Health, School of Public Health, Huazhong University of Science and Technology, Wuhan 430030, China
1 Department of Maternal and Child Health, School of Public Health, Huazhong University of Science and Technology, Wuhan 430030, China | | | Du Yukai | Department of Maternal and Child Health, School of Public Health, Huazhong University of Science and Technology, Wuhan 430030, China
1 Department of Maternal and Child Health, School of Public Health, Huazhong University of Science and Technology, Wuhan 430030, China | | | Shen Min | Department of Maternal and Child Health, School of Public Health, Huazhong University of Science and Technology, Wuhan 430030, China | shenmin@mail.hust.edu.cn |
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| Abstract: |
| 目的 了解18～59岁成年人儿童期不良经历的流行特征,探讨与成年后慢性病发病的相关性,为慢性病早期预防提供依据。方法 采用横断面研究,在湖北省麻城市龙池、南湖和鼓楼3个街道随机整群抽取18～59岁成年人,回顾性调查儿童期不良经历与成年后的慢性病患病情况,采用单因素和多因素logistic回归分析相关性。结果 共调查1 767名18～59岁成年人,其中1 501份问卷有效。男女性平均年龄分别为(36.32±10.20)岁和(35.72±9.08)岁。儿童期不良经历的发生率为66.22%,包括情感忽视(26.65%)、身体虐待(21.52%)、父母分居/离异(21.45%)、受到欺负(3.33%)、家庭物质滥用(1.53%)等。儿童期不良经历可增加成年后的慢性病发病风险,随着儿童期不良经历评分的增加,慢性病发病风险有增加趋势(Z=-5.902 1,P< 0.000 1)。多因素分析显示,家庭物质滥用(OR=2.82,95%CI:1.16～6.80)、受到欺负(OR=2.59,95%CI:1.39～4.80)、躯体虐待(OR=1.93,95%CI:1.41～2.64)和父母分居/离异(OR=1.51,95%CI:1.09～2.09)增加成年后慢性病发病风险。结论 儿童期不良经历发生率较高,可增加成年后慢性病发病风险,慢性病的早期预防应从儿童期开始。 |
| English Abstract: |
| Objective To analyze the prevalence and characteristics of childhood adverse experiences among adults aged 18-59 years and understand the association between childhood adverse experiences and risk of chronic diseases in adulthood. Methods A cross-sectional study was conducted with a questionnaire among adults aged 18-59 years selected through cluster random sampling from 3 communities in Macheng,Hubei province. Uinivariate and multivariate logistic regression analyses were conducted to evaluate the association between adverse experiences in childhood and the risk of chronic diseases in adulthood. Results A total of 1 767 adults aged 18-59 years were surveyed and 1 501 valid questionnaires were returned. The average age was (36.32±10.20) years for males and (35.72±9.08) years for females. The prevalence rate of childhood adverse experiences was 66.22%. The risk of chronic disease in adults increased with the increase of the score indicating childhood adverse experiences (Z=-5.902 1,P< 0.000 1). Multivariate logistic regression analysis showed that being physically abused (OR=1.93,95%CI:1.41-2.64),substance abuse in family (OR=2.82,95%CI:1.16-6.80),being bullied (OR=2.59,95%CI:1.39-4.80) and parents separation/divorce (OR=1.51,95%CI:1.09-2.09) were significantly associated with risk of chronic diseases in adulthood. Conclusion The prevalence of adverse childhood experiences was high in adults aged 18-59 years,which was significantly associated with the risk of chronic diseases in adulthood. Early prevention of chronic diseases should be conducted in childhood. |
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