| 翟俊伟,王晓成,王晶莹,宋泽婧,余红梅.阿尔茨海默病家庭负担影响因素分析[J].Chinese journal of Epidemiology,2015,36(9):962-966 |
| 阿尔茨海默病家庭负担影响因素分析 |
| Study on factors associated with family burden of Alzheimer's disease |
| Received:January 18, 2015 |
| DOI：10.3760/cma.j.issn.0254-6450.2015.09.012 |
| KeyWord: 阿尔茨海默病 家庭负担 家庭负担量表 |
| English Key Word: Alzheimer's disease Family burden Family Burden Scale of Diseases |
| FundProject:国家自然科学基金(81373106) |
| Author Name | Affiliation | E-mail | | Zhai Junwei | School of Public Health, Shanxi Medical University, Taiyuan 030001, China | | | Wang Xiaocheng | School of Public Health, Shanxi Medical University, Taiyuan 030001, China | | | Wang Jingying | School of Public Health, Shanxi Medical University, Taiyuan 030001, China | | | Song Zejing | School of Public Health, Shanxi Medical University, Taiyuan 030001, China | | | Yu Hongmei | School of Public Health, Shanxi Medical University, Taiyuan 030001, China | yu_hongmei@hotmail.com |
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| Abstract: |
| 目的 探讨阿尔茨海默病(AD)家庭生活负担及其影响因素。方法 采用整群抽样方法,选择太原市2家三甲医院及3个社区168例已确诊AD患者的照料者为研究对象,通过照料者负担量表(CBI)和家庭负担量表(FBS)收集信息。路径分析探讨照料者负担影响因素,家庭负担总分单因素和多因素分析分别采用t检验、单因素方差分析和多重线性回归。结果 照料者负担总分为52.41±17.07;患者的认知水平对照料者负担影响有直接效应(标准化β=-0.280,P< 0.001)和间接效应,患者的日常行为能力对照料者负担有间接效应。家庭负担总分为16.23±9.00。单因素分析显示,患者性别、年龄、文化程度、认知功能、日常行为能力、精神行为症状、抑郁和痴呆等级对FBS总分有影响(P< 0.05);多因素分析显示,影响FBS总分的因素包括患者性别(标准化 β=0.280,P< 0.01)、认知功能(标准化β=-0.158,P=0.033)以及日常行为能力(标准化β=-0.155,P=0.039)。结论 AD患者认知功能和日常行为能力对照料者及家庭负担影响较大,可据此制定措施以减轻AD患者家庭负担。 |
| English Abstract: |
| Objective To understand the family burden of Alzheimer's disease(AD) and associated factors. Methods The subjects were 168 caregivers of patients with AD selected from two class 3A hospitals and three communities in Taiyuan through cluster sampling. The data were collected by using the Caregiver Burden Inventory (CBI) and the Family Burden Scale (FBS) of diseases. Path analysis was applied to identify the factors associated with the total score of CBI. T-test and One-way analysis of variance were applied to identify the factors associated with the total score of FBS. Multiple linear regression analysis was applied to identify the factors associated with family burden of AD. Results The total score of the caregivers' burden was 52.41±17.07. AD patients' cognitive function had direct (standardized β=-0.280,P< 0.001) and indirect effect on CBI;while daily performance of AD patients had indirect effect on CBI. The total score of family burden was 16.23±9.00. Univariate analysis showed that the sex,age,education level,cognitive function,daily performance,mental status,depression and dementia rating of AD patients might affect the total score of FBS (P< 0.05). Multivariate analysis showed that the factors which affected the total score of FBS included the sex (standardized β=0.280,P< 0.01),cognitive function (standardized β=-0.158,P=0.033) and daily performance of AD patients (standardized β=-0.155,P=0.039). Conclusion The caregiver and family burden of AD was mainly associated with the cognitive function and daily performance of AD patients. It is necessary to take targeted measures to reduce the caregiver and family burden of AD. |
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