| 昌盛,白亚娜,蒲宏全,李霓,程宁,李海燕,解芝洞,李富秀,胡晓斌,朱锦兵,赫捷,代敏.金昌队列人群结直肠癌疾病负担分析[J].Chinese journal of Epidemiology,2016,37(3):325-328 |
| 金昌队列人群结直肠癌疾病负担分析 |
| Disease burden of colorectal cancer in Jinchang cohort |
| Received:October 29, 2015 |
| DOI：10.3760/cma.j.issn.0254-6450.2016.03.006 |
| KeyWord: 结直肠肿瘤 疾病负担 潜在减寿年 潜在工作损失年 队列 |
| English Key Word: Colorectal neoplasia Cancer burden Potential years of life lost Working potential years of life lost Cohort |
| FundProject:国家重大公共卫生服务项目(财社2012-64);金川集团股份有限公司科学技术项目(JKZ20120013) |
| Author Name | Affiliation | E-mail | | Chang Sheng | Department of Cancer Prevention, Program Office for Cancer Screening in Urban China, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing 100021, China | | | Bai Yana | Institute of Epidemiology and Biostatistics, School of Public Health, Center for Cancer Prevention and Control, Lanzhou University, Lanzhou 730000, China | | | Pu Hongquan | Workers' Hospital of Jinchuan Group Company Limited, Jinchang 737100, China | | | Li Ni | Department of Cancer Prevention, Program Office for Cancer Screening in Urban China, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing 100021, China | | | Cheng Ning | School of Basic Medical Sciences, Center for Cancer Prevention and Control, Lanzhou University, Lanzhou 730000, China | | | Li Haiyan | Workers' Hospital of Jinchuan Group Company Limited, Jinchang 737100, China | | | Xie Zhidong | Institute of Epidemiology and Biostatistics, School of Public Health, Center for Cancer Prevention and Control, Lanzhou University, Lanzhou 730000, China | | | Li Fuxiu | Workers' Hospital of Jinchuan Group Company Limited, Jinchang 737100, China | | | Hu Xiaobin | Institute of Epidemiology and Biostatistics, School of Public Health, Center for Cancer Prevention and Control, Lanzhou University, Lanzhou 730000, China | | | Zhu Jinbing | Workers' Hospital of Jinchuan Group Company Limited, Jinchang 737100, China | | | He Jie | Department of Cancer Prevention, Program Office for Cancer Screening in Urban China, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing 100021, China | | | Dai Min | Department of Cancer Prevention, Program Office for Cancer Screening in Urban China, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing 100021, China | daimin2002@hotmail.com |
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| Abstract: |
| 目的 评价金昌队列人群结直肠癌的疾病负担及变化趋势。方法 应用历史队列研究方法收集金昌队列人群2001－2013年结直肠癌全死因资料及2001－2010年结直肠癌住院患者病案资料,应用死亡率、标化死亡率、直接住院费用、潜在减寿年(PYLL)、人均PYLL(APYLL)、潜在工作损失年(WPYLL)以及人均WPYLL(AWPYLL)等指标描述结直肠癌造成的疾病负担状况,运用Spearman秩相关和平均增长速度分析疾病负担的变化趋势。结果 2001－2013年金昌队列人群结直肠癌粗死亡率为9.53/10万,平均年增长速度为12.89%。结直肠癌造成该队列人群PYLL、APYLL、WPYLL和AWPYLL分别为485.00人年、9.15年、253.00人年和4.77年。2001－2010年该队列人群结直肠癌住院患者人均例次直接住院费用为7 064.38元,日均直接住院费用为408.43元,均无明显增长趋势。结论 金昌队列人群结直肠癌死亡率呈上升趋势,疾病负担逐渐沉重。 |
| English Abstract: |
| Objective To evaluate the disease burden of colorectal cancer in Jinchang cohort, and provide evidence for preventing colorectal cancer and reducing the disease burden of colorectal cancer in the cohort. Methods The colorectal cancer mortality data from 2001 to 2013 and the medical records of colorectal cancer patients from 2001 to 2010 were collected for this retrospective cohort study. The colorectal cancer disease burden was described by using mortality rate, standardized mortality rate, medical expenditure, potential years of life lost (PYLL), average potential years of life lost (APYLL), working potential years of life lost (WPYLL), and average working potential years of life lost (AWPYLL). The development trend in disease burden of colorectal cancer was analyzed by using Spearman correlation and the average growth rate. Results The crude mortality rate of colorectal cancer from 2001 to 2013 was 9.53/100 000 with the average annual growth rate of 12.89%. The PYLL, APYLL, WPYLL and AWPYLL of colorectal cancer were 485.00 person-years, 9.15 years, 253.00 person-years, and 4.77 years, respectively. The direct medical expenditure due to colorectal cancer was 7 064.38 Yuan per case and 408.43 Yuan per day. There was no increasing trend in the direct medical expenditure due to colorectal cancer. Conclusion Colorectal cancer mortolity rate was on the rise and it caused heavy disease burden in Jinchang cohort. |
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