| 李敬云.艾滋病病毒1型CRF01_AE毒株的过去、现在和将来[J].Chinese journal of Epidemiology,2016,37(4):443-449 |
| 艾滋病病毒1型CRF01_AE毒株的过去、现在和将来 |
| Vision on the past, present and future of HIV-1 CRF01_AE |
| Received:January 05, 2016 |
| DOI：10.3760/cma.j.issn.0254-6450.2016.04.001 |
| KeyWord: 艾滋病病毒,1型 CRF01_AE亚型 基因亚型 重组 |
| English Key Word: HIV-1 CRF01_AE subtype Subtype Recombinant |
| FundProject:国家科技重大专项(2012ZX10001002) |
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| Abstract: |
| CRF01_AE是我国目前流行的主要HIV-1毒株,具有独特的流行病学特征。本文从该毒株的发现起源与命名、在国内外的流行过程、参与形成的重组毒株以及致病性等方面进行介绍,并讨论了与流行病学特征密切相关的社会和生物学因素。 |
| English Abstract: |
| CRF01_AE has been the major HIV-1 strain circulating in China with unique epidemiological features. In this paper, this strain is fully described on its origination, nomenclature and the feature of circulation, nationally and globally. Data on the related pathogenesis and combination with other strains are also described. In the end, social and biological factors associated with the characteristics are discussed. |
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