Abstract
李春霞,王君,潘明虎,程雁鹏,冯永亮,苏通,石璟,陈卿,石珊,王素萍.美沙酮维持治疗人群高危性行为相关因素及交互作用分析[J].Chinese journal of Epidemiology,2016,37(6):796-800
美沙酮维持治疗人群高危性行为相关因素及交互作用分析
Related factors and interaction on high-risk sexual behaviors among patients under the methadone maintenance treatment
Received:March 10, 2016  
DOI:10.3760/cma.j.issn.0254-6450.2016.06.011
KeyWord: 美沙酮维持治疗者  高危性行为  相关因素  交互作用
English Key Word: Patients under the methadone maintenance treatment  High-risk sexual behaviors  Related factors  Interaction
FundProject:国家科技重大专项(2012ZX10002001003004);山西省回国留学人员科研资助(2013056)
Author NameAffiliationE-mail
Li Chunxia Department of Epidemiology, School of Public Health, Shanxi Medical University, Taiyuan 030001, China  
Wang Jun Department of Epidemiology, School of Public Health, Shanxi Medical University, Taiyuan 030001, China  
Pan Minghu Department of Epidemiology, School of Public Health, Shanxi Medical University, Taiyuan 030001, China  
Cheng Yanpeng Department of Epidemiology, School of Public Health, Shanxi Medical University, Taiyuan 030001, China  
Feng Yongliang Department of Epidemiology, School of Public Health, Shanxi Medical University, Taiyuan 030001, China  
Su Tong Department of Epidemiology, School of Public Health, Shanxi Medical University, Taiyuan 030001, China  
Shi Jing Department of Epidemiology, School of Public Health, Shanxi Medical University, Taiyuan 030001, China  
Chen Qing Department of Epidemiology, School of Public Health, Shanxi Medical University, Taiyuan 030001, China  
Shi Shan Nanning Red Cross Hospital, Nanning 530012, China  
Wang Suping Department of Epidemiology, School of Public Health, Shanxi Medical University, Taiyuan 030001, China spwang88@163.com 
Hits: 4269
Download times: 2219
Abstract:
      目的 了解美沙酮维持治疗人群高危性行为的发生情况,并探讨相关因素。方法 对2014年9-11月在广西壮族自治区3所美沙酮维持治疗门诊的636名治疗者进行面对面问卷调查,收集其一般人口学特征、高危性行为及相关的行为因素等资料。通过χ2检验和多因素回归分析探讨高危性行为的相关因素及其交互作用。结果 636名美沙酮维持治疗者中最近3个月发生过高危性行为的比例高达80.2%(510/636)。单因素分析结果显示,性别、年龄、婚姻状况、户籍所在地、乙肝疫苗接种史、首次吸毒年龄和HIV感染可能与高危性行为的发生有关(P<0.05);多因素回归分析表明,男性、未接种乙肝疫苗/接种史不详、未感染HIV的美沙酮维持治疗者发生高危性行为的风险较高,OR值(95%CI)分别为1.668(1.021~2.725)、1.730(1.068~2.801)和2.880(1.697~4.888)。未接种乙肝疫苗/接种史不详与未感染HIV之间存在相加交互作用。结论 美沙酮维持治疗人群高危性行为的发生率较高,其相关因素为男性、未接种乙肝疫苗/接种史不详以及未感染HIV。建议加强对美沙酮维持治疗者的干预,降低高危性行为的发生。
English Abstract:
      Objective To estimate the incidence of high-risk sexual behaviors and to explore the related factors among patients receiving methadone maintenance treatment. Methods Face to face interviews were conducted on 636 patients at 3 methadone maintenance treatment clinics in Guangxi Zhuang Autonomous Region, in China, from September to November, 2014. General demographic characteristics and behavioral factors associated with high-risk sexual behavior of patients were collected through questionnaires. Both univariate and multivariate logistic regression analysis were used to analyze the related factors of high-risk sexual behaviors and the interactions between them. Results 636 participants were included in this study. Majority of the patients (80.2%) practiced high-risk sexual behaviors in the past three months. Data from the univariate analysis showed that factors as:gender, age, marital status, registered residence, history of hepatitis B (HepB) vaccination, age started drug use and HIV infection etc. might be associated with high-risk sexual behaviors (P<0.05). Data from the multivariate logistic regression analysis showed that factors as:being male, histories with non-or unknown HepB vaccination and free of HIV infection etc., were likely to have high-risk sexual behaviors, with OR (95%CI) as 1.668 (1.021-2.725), 1.730 (1.068-2.801) and 2.880 (1.697-4.888), respectively. Additive interactions were observed between non-or unknown histories of HepB vaccination and free of HIV infection. Conclusion The incidence rates on high-risk sexual behaviors appeared high in patients under the methadone maintenance treatment. Patients with factors as:being male, histories with non-or unknown HepB vaccination and free of HIV infection were significantly associated with high-risk sexual behaviors. It is necessary to emphasize on behavioral intervention among patients under the methadone maintenance treatment, in order to reduce the occurrence of high-risk sexual behaviors.
View Fulltext   Html FullText     View/Add Comment  Download reader
Close