Abstract
林春燕,王明昌,曾小平,邝仕壮,林先博.海口市2008-2015年手足口病流行病学特征分析[J].Chinese journal of Epidemiology,2016,37(12):1615-1618
海口市2008-2015年手足口病流行病学特征分析
Epidemiologic features of hand-foot-mouth disease in Haikou city from 2008 to 2015
Received:June 20, 2016  
DOI:10.3760/cma.j.issn.0254-6450.2016.12.012
KeyWord: 手足口病  流行病学特征  病原学监测
English Key Word: Hand-foot-mouth disease  Epidemiological characteristics  Etiological surveillance
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Author NameAffiliationE-mail
Lin Chunyan Infectious Disease Prevention and Control Department, Haikou Center for Disease Control and Prevention, Haikou 571100, China
Key Laboratory for Infectious Disease Monitoring and Early Warning(Haikou) Research Base of Chinese Center for Disease Control and Prevention, Haikou Center for Disease Control and Prevention, Haikou 571100, China 
cy6989@sina.com 
Wang Mingchang Infectious Disease Prevention and Control Department, Haikou Center for Disease Control and Prevention, Haikou 571100, China
Key Laboratory for Infectious Disease Monitoring and Early Warning(Haikou) Research Base of Chinese Center for Disease Control and Prevention, Haikou Center for Disease Control and Prevention, Haikou 571100, China 
 
Zeng Xiaoping Infectious Disease Prevention and Control Department, Haikou Center for Disease Control and Prevention, Haikou 571100, China
Key Laboratory for Infectious Disease Monitoring and Early Warning(Haikou) Research Base of Chinese Center for Disease Control and Prevention, Haikou Center for Disease Control and Prevention, Haikou 571100, China 
 
Kuang Shizhuang Microbial Laboratory, Haikou Center for Disease Control and Prevention, Haikou 571100, China  
Lin Xianbo Infectious Disease Prevention and Control Department, Haikou Center for Disease Control and Prevention, Haikou 571100, China  
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Abstract:
      目的 分析2008-2015年海口市手足口病流行病学特征。方法 用描述性流行病学方法对2008-2015年海口市手足口病发病资料和病原学检测情况资料进行统计分析。结果 2008-2015年海口市共报告手足口病71 611例,其中报告重症病例728例,重症百分比为1.02%。年平均发病率为 458.89/10万,年发病率总体呈上升趋势。死亡11例,年均死亡率为0.07/10万。发病高峰在4-7月和9-11月。病例以≤5岁儿童为主,占总病例数的95.78%;1~岁组发病率(12 881.24/10万)最高;男性报告发病率高于女性。全市4个区均有病例报告,病例主要为散居儿童,占报告总病例数的79.89%。引起手足口病流行的病原为肠道病毒71型(EV71)、柯萨奇病毒A组16型(Cox A16)及其他肠道病毒,2011年后呈现交替流行态势。结论 海口市是我国手足口病高发地区,近年发病率呈现上升趋势,应加强监测、传染源管理、健康教育以及重点人群的综合防控。
English Abstract:
      Objective To analyze the epidemiologic features of hand-foot-mouth disease (HFMD) in Haikou city from 2008 to 2015. Methods Descriptive methods on epidemiology and detection on pathogens were conducted in Haikou city from 2008 to 2015. Results A total of 71 611 patients were diagnosed as HFMD in Haikou city from 2008 to 2015, including 728 severe cases, accounting for 1.02% among all the cases. The average annual incidence was 458.89/100 000. A total of 11 deaths were caused by the disease, with the average annual mortality rate as 0.07/100 000. Two peaks of incidence were seen, from April to July and from September to November. Age of the patients mainly fell in children aged 5 and below, taking up 95.78% of the total cases. Among all the patients, 1-year-olds presented the highest incidence as 12 881.24/100 000. The reported incidence for males was higher than that in females. There were 4 districts in Haikou city that reported the disease. Residential areas of the patients were scattered around, with a percentage of 79.89%. Spectrums of pathogens that causing the prevalence of HFMD were EV71 type, Cox A16 type and other enteroviruses, which prevailing in turns, since 2011. Conclusions Haikou city had been an area with high incidence of HFMD. The incidence started to show a rising trend recently. It is suggested that programs as surveillance, case management, health education and comprehensive prevention and control of disease on HFMD targeting on key population should be intensively implemented to reduce the mortality of the disease.
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