隐匿性乙型肝炎病毒感染研究进展

黄象艳; 石庆芬; 黄涛

Abstract

黄象艳,石庆芬,黄涛.隐匿性乙型肝炎病毒感染研究进展[J].Chinese journal of Epidemiology,2017,38(5):688-692

隐匿性乙型肝炎病毒感染研究进展

Progress in research of occult hepatitis B virus infection

Received:December 05, 2016

DOI：10.3760/cma.j.issn.0254-6450.2017.05.027

KeyWord: 隐匿性乙型肝炎病毒感染致病机制流行率

English Key Word: Occult hepatitis B virus infection Pathogenesis Prevalence

FundProject:国家自然科学基金（81101321）

Author Name	Affiliation	E-mail
Huang Xiangyan	Department of Blood Transfusion, the General Hospital of Jinan Military Command, Jinan 250031, China
Shi Qingfen	Department of Laboratory Diagnostics, Jinan Infectious Disease Hospital, Jinan 250021, China
Huang Tao	Institute for AIDS Control and Prevention, Shandong Provincial Center for Disease Control and Prevention, Jinan 250014, China	huangtao29@163.com

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Abstract:

隐匿性HBV感染（OBI）已成为世界性公共卫生问题之一，严重影响乙型肝炎的临床诊断并威胁到输血安全。本文分析近年来关于OBI的概念、致病机制、在健康人群和不同患者中的流行率以及传播可能性方面的研究数据，结果显示OBI在健康人群及不同患者中均存在一定的流行率，并可能通过输血等途径传播，应引起重视。

English Abstract:

Occult hepatitis B virus infection is a worldwide public health problem, which seriously affects the clinical diagnosis of hepatitis B and threatens the safety of blood transfusion. The concept of occult hepatitis B virus infection, the pathogenesis of occult hepatitis B virus infection, the prevalence of occult hepatitis B virus infection in different groups, including healthy population and different patients, and the possibility of transmission were summarized. The prevalence of occult hepatitis B virus infection was found in healthy population and different patients, and there is possibility of occult hepatitis B virus infection to be transmitted through blood transfusion. The paper provides a comprehensive introduction of the pathogenesis and prevalence of occult hepatitis B virus infection. More attention should be paid to occult hepatitis B virus infection.

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