新疆喀什地区维吾尔族人群糖尿病患病情况及相关危险因素研究

张周斌; 薛振香; 汪慧; 王童敏; 利耀辉; 宋雪莲; 晁先锋; 王岗; 吴雪霁; 乃孜班木·努尔麦麦提; 阿依夏穆姑丽·巴吾顿; 古丽巴哈·艾力亚斯; 周自严; 孙宝山; 王玉忠; 王鸣

Abstract

张周斌,薛振香,汪慧,王童敏,利耀辉,宋雪莲,晁先锋,王岗,吴雪霁,乃孜班木·努尔麦麦提,阿依夏穆姑丽·巴吾顿,古丽巴哈·艾力亚斯,周自严,孙宝山,王玉忠,王鸣.新疆喀什地区维吾尔族人群糖尿病患病情况及相关危险因素研究[J].Chinese journal of Epidemiology,2017,38(6):696-701

新疆喀什地区维吾尔族人群糖尿病患病情况及相关危险因素研究

Prevalence of diabetes mellitus and associated risk factors in Uygur population in Kashgar area of Xinjiang Uygur Autonomous Region

Received:December 21, 2016

DOI：10.3760/cma.j.issn.0254-6450.2017.06.002

KeyWord: 维吾尔族糖尿病空腹血糖受损患病率危险因素

English Key Word: Uygur Diabetes mellitus Impaired fasting glucose Prevalence Risk factor

FundProject:国家科技重大专项（2012ZX10004213005）；广州市医学重点学科建设项目（2017-2019-07）；广东省科技计划项目（2014A020209006）

Author Name	Affiliation	E-mail
Zhang Zhoubin	Office of Director, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China
Xue Zhenxiang	Immunization Programme Section, Shufu Center for Disease Control and Prevention, Kashgar 844100, China
Wang Hui	Department of Infectious Disease, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China
Wang Tongmin	Department of Immunization Programme, Kashgar Prefecture Center for Disease Control and Prevention, Kashgar 844100, China
Li Yaohui	Department of Immunization Programme, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China
Song Xuelian	Immunization Programme Section, Shufu Center for Disease Control and Prevention, Kashgar 844100, China
Chao Xianfeng	Immunization Programme Section, Shufu Center for Disease Control and Prevention, Kashgar 844100, China
Wang Gang	Shufu Health Bureau, Kashgar 844100, China
Wu Xueji	Department of Immunization Programme, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China
Nazibam·Nurmamat	Immunization Programme Section, Shufu Center for Disease Control and Prevention, Kashgar 844100, China
Ayxamgul·Bawudun	Immunization Programme Section, Shufu Center for Disease Control and Prevention, Kashgar 844100, China
Gulbahar·Elyas	Immunization Programme Section, Shufu Center for Disease Control and Prevention, Kashgar 844100, China
Zhou Ziyan	Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China
Sun Baoshan	The Front Command of Guangdong Province for the Work of Assistance to Xinjiang, Kashgar 844100, China Department of Disease Control and Prevention, Health and Family Planning Commission of Guangdong Province, Guangzhou 510060, China
Wang Yuzhong	Shufu Health Bureau, Kashgar 844100, China
Wang Ming	Office of Director, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China	wangming@gzcdc.org.cn

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Abstract:

目的了解新疆喀什地区维吾尔族人群糖尿病流行状况并探讨患病危险因素，为糖尿病三级预防提供参考依据。方法采用分层整群抽样方法，对新疆喀什地区疏附县≥18岁维吾尔族居民进行调查。调查方式包括问卷调查、人体测量及生化指标检测。比较不同年龄、性别人群糖尿病流行状况，采用logistic回归分析糖尿病患病的影响因素。结果共纳入研究对象4 608人，男性、女性及全人群患病率分别为13.65%、10.04%和11.31%，年龄标化率为12.34%、9.83%及10.59%。糖尿病患病率及空腹血糖受损（IFG）率随着年龄的增加而升高，60岁前多表现为糖尿病患病率低于IFG率，60岁以上呈现糖尿病患病率高于IFG率的趋势，女性人群中尤为明显。糖尿病知晓率、治疗率、控制率分别为28.02%、21.31%及5.57%。多因素分析显示：45～岁、55～岁、>65岁人群糖尿病的患病风险明显增高，OR值男性分别为2.08（95% CI：1.24～3.48）、2.73（95% CI：1.63～4.56）和3.90（95% CI：2.24～6.78），女性分别为2.63（95% CI：1.71～4.02）、3.14（95% CI：2.00～4.94）和5.56（95% CI：3.47～8.92）。有糖尿病家族史（男：OR=2.88，95% CI：1.45～5.72；女：OR=2.52，95% CI：1.49～4.26）、BMI≥28.0 kg/m²（男：OR=1.77， 95% CI：1.19～2.64；女：OR=1.80， 95% CI：1.30～2.50）等是影响糖尿病患病的危险因素。结论新疆喀什地区维吾尔族人群糖尿病患病率高，知晓率、治疗率和控制率低，应提高糖尿病检出率并针对当地糖尿病流行特点采取有针对性的防治策略及措施。

English Abstract:

Objective To investigate the epidemiologic characteristics of diabetes mellitus (DM) in Uygur residents in Kashgar of Xinjiang. Methods The survey was conducted among the Uygur residents aged ≥ 18 years selected through stratified cluster sampling in Kashgar by means of questionnaire survey, physical examination and basic laboratory test. The prevalence of different groups were calculated and risk factors of DM was analyzed by logistic vegression model. Results A total of 4 608 adults were surveyed. The prevalence of DM was 11.31% (standardized prevalence:10.59%) and the prevalence was 13.65% (standardized prevalence:12.34%) in males and 10.04% (standardized prevalence:9.83%) in females. The prevalence increased with age. The prevalence of DM was higher than the prevalence of impaired fasting glucose (IFG) in people aged >60 years, especially in females. The rates of awareness, treatment and control of DM were 28.02%, 21.31% and 5.57%, respectively. Multivariate logistic regression analysis indicated that people aged 45-55, 55-65 and >65 years had higher risk of DM and the odds ratio were 2.08 (95%CI:1.24-3.48), 2.73 (95%CI:1.63-4.56) and 3.90 (95%CI:2.24-6.78) for men and 2.63 (95% CI:1.71-4.02), 3.14 (95%CI:2.00-4.94) and 5.56 (95%CI:3.47-8.92) for woman, respectively. Family history of DM (OR=2.88 for men,95%CI:1.45-5.72; OR=2.52 for women, 95%CI:1.49-4.26) and BMI ≥ 28.0 kg/m² (OR=1.77 for men, 95%CI:1.19-2.64, OR=1.80 for women, 95%CI:1.30-2.50) were also risk factors for DM. Conclusion The prevalence of DM was high in Uygur residents in Kashgar, but the rate of awareness, treatment and control of DM were low. It is necessary to improve the detection rate of DM and conduct targeted prevention and control of DM.

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