深圳市1995-2014年住院恶性肿瘤病例疾病谱和病死率分析

王兴鲍; 洪烈城; 魏雅臻; 符霞; 鲍雪琴; 张进; 胡钢; 吴思晗; 程锦泉

Abstract

王兴鲍,洪烈城,魏雅臻,符霞,鲍雪琴,张进,胡钢,吴思晗,程锦泉.深圳市1995-2014年住院恶性肿瘤病例疾病谱和病死率分析[J].Chinese journal of Epidemiology,2017,38(6):784-788

深圳市1995-2014年住院恶性肿瘤病例疾病谱和病死率分析

Spectrum and case fatality of inpatients with malignant tumors from 1995 to 2014 in Shenzhen city

Received:November 25, 2016

DOI：10.3760/cma.j.issn.0254-6450.2017.06.019

KeyWord: 住院恶性肿瘤疾病谱病死率

English Key Word: Hospitalization Malignancy Disease spectrum Case fatality rate

FundProject:

Author Name	Affiliation	E-mail
Wang Xingbao	School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China
Hong Liecheng	School of Public Health, Southern Medical University, Guangzhou 510515, China
Wei Yazhen	School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China
Fu Xia	School of Public Health, Southern Medical University, Guangzhou 510515, China
Bao Xueqin	School of Public Health, Zhengzhou University, Zhengzhou 450001, China
Zhang Jin	School of Public Health, Southern Medical University, Guangzhou 510515, China
Hu Gang	School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China
Wu Sihan	School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China
Cheng Jinquan	Shenzhen Center for Disease Control and Prevention, Shenzhen 518055, China	cjinquan@szcdc.net

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Abstract:

目的通过对1995－2014年深圳市住院恶性肿瘤病例进行疾病谱及病死率的分析，为本地区恶性肿瘤防治工作提供科学依据。方法对1995－2014年深圳市恶性肿瘤住院及死亡情况进行监测，并采用SPSS 20.0软件对数据进行统计学分析。结果 1995－2014年深圳市共报告因恶性肿瘤住院病例160 988例，住院恶性肿瘤前三位依次为肺癌（13.64%）、肝癌（11.13%）、乳腺癌（7.86%）。20年间恶性肿瘤住院人数呈快速增长态势，2014年恶性肿瘤住院病例数是1995年的12.3倍。恶性肿瘤死亡总数19 460例，恶性肿瘤死亡前三位依次为肺癌（24.40%）、肝癌（19.84%）、结肠直肠癌（8.63%），20年间死亡人数也呈增长趋势，2014年死亡数是1995年的12.5倍。恶性肿瘤总病死率为12.09%。1995－2003年深圳市恶性肿瘤病死率年度变化百分比（APC）为9.7%（95% CI：2.0%～18.0%），呈上升趋势（t=2.72，P<0.05），2003－2014年深圳市恶性肿瘤病死率APC=-3.4%（95% CI：-7.6%～1.1%），下降趋势无统计学意义（t=-1.63，P>0.05）。住院恶性肿瘤病死率前三位依次为肺癌（21.62%）、肝癌（21.39%）、食道癌（16.50%）。20年间白血病和肝癌病死率有所下降，肺癌、食道癌、胃癌、乳腺癌、结肠直肠癌及鼻咽癌病死率均有所增加。男性病死人数明显多于女性（χ²=41.691，P<0.01），男∶女为1.65∶1。从35岁开始恶性肿瘤死亡人数显著增高，60岁后达到高峰。结论恶性肿瘤住院及死亡病例逐年增加，病死率呈上升趋势，肺癌、肝癌恶性肿瘤死因位居前列，恶性肿瘤死亡集中在中老年人群。因此，应加强对肺癌、肝癌等重点癌种的防治工作。

English Abstract:

Objective To analyze the epidemiological features, spectrum and case fatality of malignant tumor patients in Shenzhen city, to provide evidence for the development of prevention and treatment strategies on malignant tumor in Shenzhen. Methods All the hospitalized malignant tumor patients including deaths, were monitored from 1995 to 2014 in Shenzhen, and data was analyzed by SPSS 20.0 software. Results There were 160 988 inpatients of malignant tumors between 1995 and 2014 in Shenzhen. The top three hospitalized tumors were lung (13.64%), liver (11.13%) and breast (7.86%) cancers. Numbers of the malignant tumor inpatients had been rapidly increasing during the past 20 years, 12.3 times in 2014 higher than in 1995. The total number of deaths due to malignant tumors was 19 460. Deaths of the top three malignant tumors were lung (24.40%), liver (19.84%) and colorectal (8.63%) cancers and the number of deaths was increasing, 12.5 times higher in 2014 than in 1995. The overall case fatality rate was 12.09%. The annual percent change (APC) of malignant tumors case fatality rate was 9.7%(95%CI:2.0%-18.0%), during 1995-2003, with an increasing trend (t=2.72, P<0.05). The APC of case fatality rate during 2003-2014 was -3.4%(95%CI:-7.6%-1.1%), but the decreasing trend (t=-1.63, P>0.05) was not statistically significant. The top three major malignant tumors related to case fatality rate were lung cancer (21.62%), liver cancer (21.39%), and esophageal cancer (16.50%). The case fatality rates of leukemia and liver cancer had decreased during the past 20 years. The case fatality rates of cancers in lung, esophagus, stomach, breast, colorectal and nasopharyngeal, had all increased. The number of male patients was significantly exceeding the females (χ²=41.691, P<0.01), with sex ratio as 1.65:1. From age 35 and on, the number of deaths due to malignant tumors increased significantly, with the peak after 60 years of age. Conclusions The number of malignant tumor inpatients had an annual increase as well as the case fatality rate. Cancers in lung, liver appeared the leading causes of death among the malignant tumor patients, with elderly in particular. Strategies related to the prevention and treatment of cancers in lung, liver should be strengthened.

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