| 江震,斗智,阎志华,宋炜路,陈韵,任仙龙,陈军,曹巍,徐杰,吴尊友.数据缺失对中国16个大城市MSM人群HIV感染者病毒载量抽样调查结果的影响[J].Chinese journal of Epidemiology,2017,38(9):1169-1173 |
| 数据缺失对中国16个大城市MSM人群HIV感染者病毒载量抽样调查结果的影响 |
| Effect of data missing on population based viral load survey in HIV infected men who have sex with men sampled in 16 large cities, China |
| Received:January 20, 2017 |
| DOI：10.3760/cma.j.issn.0254-6450.2017.09.005 |
| KeyWord: 艾滋病病毒 病毒载量 男男性行为人群 数据缺失 |
| English Key Word: HIV Viral load Men who have sex with men Missing data |
| FundProject:国家科技重大专项（2012ZX10001007005） |
| Author Name | Affiliation | E-mail | | Jiang Zhen | Division of Prevention and Intervention, National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and Prevention, Beijing 102206, China | | | Dou Zhi | Division of Prevention and Intervention, National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and Prevention, Beijing 102206, China | | | Yan Zhihua | Division of Prevention and Intervention, National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and Prevention, Beijing 102206, China | | | Song Weilu | Division of Prevention and Intervention, National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and Prevention, Beijing 102206, China | | | Chen Yun | Division of Prevention and Intervention, National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and Prevention, Beijing 102206, China | | | Ren Xianlong | Division of Prevention and Intervention, National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and Prevention, Beijing 102206, China | | | Chen Jun | School of Public Health, Anhui Medical University, Hefei 230032, China | | | Cao Wei | School of Public Health, Anhui Medical University, Hefei 230032, China | | | Xu Jie | Division of Prevention and Intervention, National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and Prevention, Beijing 102206, China | xujie@chinaaids.cn | | Wu Zunyou | National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China | |
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| Abstract: |
| 目的 分析我国MSM人群HIV感染者（MSM感染者）病毒载量（VL）抽样调查数据缺失及对调查结果的影响。方法 利用国家科技重大专项课题2013-2015年在北京、上海、南京、杭州、武汉、重庆、昆明、西安、广州、深圳、南宁、乌鲁木齐、哈尔滨、长春、成都和天津16个大城市MSM人群中开展的HIV感染者VL抽样调查数据库，采用SPSS 17.0软件对VL缺失数据进行描述性分析。结果 在12 150名随机抽样的MSM感染者中，75.2%（9 141/12 150）调查对象接受了VL数据收集，24.8%（3 009/12 150）调查对象VL数据缺失；目前正在接受抗病毒治疗与未接受抗病毒治疗者缺失率分别为11.5%（765/6 675）、39.4%（2 060/5 223）；本地与外地户籍VL数据缺失率分别为21.9%（1 866/8 523）、28.4%（959/3 374）。结论 MSM感染者VL抽样调查存在一定比例的数据缺失，抗病毒治疗和户籍是VL数据缺失的主要影响因素，VL数据缺失会对准确评价MSM感染者社区病毒载量水平和人群病毒载量水平造成影响。 |
| English Abstract: |
| Objective To analyze the effect of missing data in population based viral load (PVL) survey in HIV infected men who have sex with men (MSM) sampled in 16 cities in China. Methods The database of 3 virus load sampling survey conducted consecutively in HIV infected MSM population in 16 large cities (Beijing, Shanghai, Nanjing, Hangzhou, Wuhan, Chongqing, Kunming, Xi'an, Guangzhou, Shenzhen, Nanning, Urumuqi, Harbin, Changchun, Chengdu and Tianjin) during 2013-2015 was used. SPSS 17.0 software was used to describe distribution of the missing data and analyze associated factors. Results A total of 12 150 HIV infected MSM were randomly selected for the surveys, in whom, 9 141 (75.2%) received virus load tests, while 3 009 (24.8%) received no virus load tests, whose virus load data missed. The virus load data missing rates in MSM with or without access to antiretroviral therapy (ART) were 11.5% (765/6 675) and 39.4% (2 060/5 223) respectively, and the virus load data missing rates were 21.9% (1 866/8 523) and 28.4% (959/3 374), respectively, in local residents and non-local residents (migrants). Conclusions The analysis indicated that the data missing occurred in the virus load survey in HIV infected MSM population. ART status and census registering status were the main influencing factors. Data missing could influence the accurate evaluation of community viral load (CVL) and population viral load (PVL) levels in HIV infected MSM in China. |
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