Abstract
王梦莹,唐迅,秦雪英,武轶群,李劲,高培,黄少平,李娜,杨冬立,任涛,吴涛,陈大方,胡永华.北方农村地区居民常见慢性非传染性疾病的家系队列研究进展[J].Chinese journal of Epidemiology,2018,39(1):94-97
北方农村地区居民常见慢性非传染性疾病的家系队列研究进展
Progress in research of family-based cohort study on common chronic non-communicable diseases in rural population in northern China
Received:July 14, 2017  
DOI:10.3760/cma.j.issn.0254-6450.2018.01.020
KeyWord: 高血压  脑卒中  糖尿病  家系队列研究
English Key Word: Hypertension  Stroke  Diabetes mellitus  Family-based cohort study
FundProject:国家自然科学基金(81230066,81102177,81172744,81473043)
Author NameAffiliationE-mail
Wang Mengying Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China  
Tang Xun Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China  
Qin Xueying Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China  
Wu Yiqun Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China  
Li Jin Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China  
Gao Pei Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China  
Huang Shaoping General Office, Fangshan District Center for Disease Control and Prevention, Beijing 102401, China  
Li Na General Office, Fangshan District Center for Disease Control and Prevention, Beijing 102401, China  
Yang Dongli General Office, Fangshan District Health Bureau, Beijing 102401, China  
Ren Tao Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China  
Wu Tao Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China  
Chen Dafang Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China  
Hu Yonghua Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China yhhu@bjmu.edu.cn 
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Abstract:
      家系队列研究是一种特殊的队列研究方法,以家系为单位收集研究对象的生物样本和环境暴露信息,并进行随访,为探索复杂性疾病病因研究中遗传、环境、基因-基因和基因-环境交互作用提供重要资源。本文将对“北方农村地区居民常见慢性非传染性疾病的家系队列研究”的目标、方法、初步结果、机遇与挑战进行简单介绍。
English Abstract:
      Family-based cohort study is a special type of study design, in which biological samples and environmental exposure information of the member in a family are collected and related follow up is conducted. Family-based cohort study can be applied to explore the effect of genetic factors, environmental factors, gene-gene interaction, and gene-environment interaction in the etiology of complex diseases. This paper summarizes the objectives, methods and results, as well as the opportunities and challenges of the family-based cohort study on common chronic non-communicable diseases in rural population in northern China.
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