| 吕晓珍,孙凤,詹思延.偏倚风险评估系列:(四)整群设计随机对照试验[J].Chinese journal of Epidemiology,2018,39(2):240-244 |
| 偏倚风险评估系列:(四)整群设计随机对照试验 |
| Risk related to bias assessment: (4) Revised Cochrane Risk of Bias Tool for cluster-randomized control trials (RoB2.0) |
| Received:July 12, 2017 |
| DOI：10.3760/cma.j.issn.0254-6450.2018.02.020 |
| KeyWord: 偏倚风险 评估工具 随机对照试验 整群设计 系统综述 |
| English Key Word: Risk of bias Tool for assessment Randomized controlled trial Cluster-randomized design Systematic review |
| FundProject:国家自然科学基金（71673003）；首都卫生发展科研专项（首发2016-4-116） |
| Author Name | Affiliation | E-mail | | Lyu Xiaozhen | Peking University Institute of Mental Health, Key Laboratory of Mental Health, Ministry of Health, Beijing Municipal Key Laboratory for Translational Research on Diagnosis and Treatment of Dementia, Beijing 100191, China | | | Sun Feng | Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China | sunfeng@bjmu.edu.cn | | Zhan Siyan | Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China | |
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| Abstract: |
| 介绍整群设计随机对照试验Cochrane偏倚评估工具2.0版本（RoB2.0）的主要内容，阐述与平行设计RoB2.0的不同之处，并举例说明整群设计RoB2.0的使用方法和注意事项。RoB2.0针对整群设计的自身特点，设置了相应的信号问题，为将整群设计试验纳入系统综述进行证据整合提供偏倚风险信息。 |
| English Abstract: |
| This paper introduced the Revised Cochrane Risk of Bias Tool RoB2.0 for cluster-randomized control trials (CRCT) and compared RoB2.0 of CRCT with individually randomized, parallel group trials, and illustrated the application of RoB2.0 for CRCT in a published CRCT. Special signal questions were designed for CRCT according to its specialty that different from individually randomized, parallel group trials in RoB2.0 and also providing information on risk of bias about CRCT in systematic reviews for the synthesis of evidence. |
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