| 张磊,邵中军.HBV宫内传播研究在乙型肝炎防控工作中发挥着重要的作用[J].Chinese journal of Epidemiology,2019,40(9):1055-1058 |
| HBV宫内传播研究在乙型肝炎防控工作中发挥着重要的作用 |
| Important role of study on intrauterine transmission of HBV in prevention and control of hepatitis B |
| Received:January 31, 2019 |
| DOI：10.3760/cma.j.issn.0254-6450.2019.09.007 |
| KeyWord: 乙型肝炎病毒 宫内传播 显性感染 隐匿性感染 |
| English Key Word: HBV Intrauterine transmission Dominate infection Occult infection |
| FundProject:国家自然科学基金（81102140，81472988，81373058，81773488）；陕西省重点研发计划（2018SF-166） |
| Author Name | Affiliation | E-mail | | Zhang Lei | Department of Epidemiology, Key Laboratory of Hazard Assessment and Control in Special Operational Environment of Ministry of Education, School of Military Preventive Medicine, Air Force Military Medical University, Xi'an 710032, China | drzhanglei@fmmu.edu.cn | | Shao Zhongjun | Department of Epidemiology, Key Laboratory of Hazard Assessment and Control in Special Operational Environment of Ministry of Education, School of Military Preventive Medicine, Air Force Military Medical University, Xi'an 710032, China | |
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| Abstract: |
| 全新的HBV宫内传播研究包括了宫内显性感染和宫内隐匿性感染，HBV宫内显性感染即传统意义上的HBV宫内感染，虽然HBV宫内感染历经了几十年的研究，但是干预效果甚微，导致母婴传播成为乙型肝炎（乙肝）主要的传播途径。随着科学技术的发展，人们更多认识到HBV宫内隐匿性感染，使得HBV宫内传播的定义得到进一步完善和拓展，HBV宫内隐匿性感染的研究将填补HBV垂直传播防控的空白领域，拓展的新研究角度将决定乙肝防控新的决策方向和内容，为我国乙肝预防控制工作发挥重要作用。 |
| English Abstract: |
| The new research of intrauterine transmission of HBV includes intrauterine dominant infection and occult infection. Intrauterine dominant infection of HBV is the traditional intrauterine infection. Although intrauterine infection of HBV has been studied for decades, the intervention effects on HBV infection are very limited. As a result, mother to child transmission has become the main route of the transmission of HBV. With the development of science and technology, people's understand of intrauterine occult infection of HBV has been deepened, and the definition of intrauterine transmission of HBV has been further completed and expanded. The study of intrauterine occult infection of HBV will play an important role in prevention and control of hepatitis B in China through filling in a gap in the field of prevention and control of vertical transmission of HBV, exploring new research perspective and providing guideline for related decision-making. |
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