| 魏锣沛,李霓,王刚,温艳,吕章艳,冯小双,李鑫,陈玉恒,陈宏达,陈朔华,任建松,石菊芳,崔宏,吴寿岭,代敏,赫捷.身体测量指标与胃癌发病风险的流行病学研究进展[J].Chinese journal of Epidemiology,2019,40(11):1481-1486 |
| 身体测量指标与胃癌发病风险的流行病学研究进展 |
| Progress in epidemiologic research of association between anthropometric indicators and risk for gastric cancer |
| Received:April 24, 2019 |
| DOI：10.3760/cma.j.issn.0254-6450.2019.11.025 |
| KeyWord: 肿瘤，胃 身体测量指标 流行病学 |
| English Key Word: Neoplasm, stomach Anthropometry Epidemiology |
| FundProject:国家重点研发计划（2016YFC1302500，2016YFC1302503）；北京市优秀人才培养资助（2017000021223TD05）；国家自然科学基金（81673265，81871885）；协和青年基金（2017320013）；中国医学科学院中央级公益性科研院所基本科研业务费（2018RC330002，2018RC320010） |
| Author Name | Affiliation | E-mail | | Wei Luopei | Office for Cancer Early Diagnosis and Treatment, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China | | | Li Ni | Office for Cancer Early Diagnosis and Treatment, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China | | | Wang Gang | Department of Oncology, Kailuan General Hospital, Tangshan 063000, China | | | Wen Yan | Office for Cancer Early Diagnosis and Treatment, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China | | | Lyu Zhangyan | Office for Cancer Early Diagnosis and Treatment, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China | | | Feng Xiaoshuang | Office for Cancer Early Diagnosis and Treatment, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China | | | Li Xin | Office for Cancer Early Diagnosis and Treatment, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China | | | Chen Yuheng | Office for Cancer Early Diagnosis and Treatment, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China | | | Chen Hongda | Office for Cancer Early Diagnosis and Treatment, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China | | | Chen Shuohua | Health Department of Kailuan(Group), Tangshan 063000, China | | | Ren Jiansong | Office for Cancer Early Diagnosis and Treatment, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China | | | Shi Jufang | Office for Cancer Early Diagnosis and Treatment, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China | | | Cui Hong | Office for Cancer Early Diagnosis and Treatment, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China | | | Wu Shouling | Health Department of Kailuan(Group), Tangshan 063000, China | | | Dai Min | Office for Cancer Early Diagnosis and Treatment, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China | daimin2002@hotmail.com | | He Jie | Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China Wei Luopei and Li Ni contributed equally to this article | |
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| Abstract: |
| 胃癌是严重威胁人类健康的最重要恶性肿瘤之一。流行病学研究提示，身体测量指标与胃癌发病可能存在关联，目前研究结果尚不一致。本文通过查阅PubMed、万方数据知识服务平台等数据库文献，系统回顾了国内外关于身体测量指标与消化系统恶性肿瘤发病关系的前瞻性队列研究，并进行总结，结果显示，全身性肥胖和腹型肥胖可能与贲门癌发病风险相关，体重过轻与胃癌发病关联需进一步确证。本文从身体测量指标角度出发综述了胃癌发病的研究进展，以期为该领域未来研究方向提供思路，并为人群的胃癌防治提供科学依据。 |
| English Abstract: |
| Gastric cancer is one of the most common cancer. Studies have been conducted to evaluate the association between anthropometric indicators and gastric cancer, but the results were inconsistent. Therefore, a literature retrieval was conducted by using PubMed and Wanfang databases to summarize the latest research progress in the cohort study of the association between anthropometric indicators and the risk for gastric cancer. It was found that both general obesity and abdominal obesity might increase the risk for gastric cancer, while the association between underweight and gastric cancer needs further study. This paper summarizes the progress in the cohort study of association between anthropometric indicators for the risk for gastric cancer in order to provide evidence for the prevention and control of gastric cancer. |
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