| 张晗希,韩孟杰,周郁,修翔飞,徐芳,王璐.我国50岁及以上人群HIV感染率的Meta分析[J].Chinese journal of Epidemiology,2020,41(1):96-102 |
| 我国50岁及以上人群HIV感染率的Meta分析 |
| HIV infection rate in people aged 50 years and older in China: a Meta-analysis |
| Received:April 23, 2019 |
| DOI：10.3760/cma.j.issn.0254-6450.2020.01.018 |
| KeyWord: 艾滋病病毒 感染 Meta分析 50岁及以上人群 |
| English Key Word: HIV Infection Meta-analysis People aged 50 years and above |
| FundProject: |
| Author Name | Affiliation | E-mail | | Zhang Hanxi | National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China | | | Han Mengjie | National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China | | | Zhou Yu | National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China | | | Xiu Xiangfei | National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China | | | Xu Fang | National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China | | | Wang Lu | National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China | wanglu64@163.com |
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| Abstract: |
| 目的 我国≥ 50岁人群艾滋病疫情呈上升趋势，已成为艾滋病防治的关注重点。本研究运用Meta分析法综合评估我国≥ 50岁人群HIV感染状况及其时间和地区分布，为该人群艾滋病预防干预提供科学依据。方法 文献检索数据库包括万方数据资源系统、中国期刊全文数据库（CNKI）、PubMed和Embase数据库。对各数据库所检索出的文章进行筛选和数据提取，运用R Studio1.1.456软件计算合并HIV感染率，并评估发表偏倚。结果 本研究共纳入30篇文献，研究地区覆盖全国13个省（市、自治区）。结果显示，2010-2018年≥ 50岁人群HIV感染率为1.68%（95%CI：1.00%~2.79%）。按照地区进行亚组分析中，东部地区HIV感染率（2.60%）高于中、西部地区（0.16%、2.13%）。结论 我国≥ 50岁人群HIV感染率总体较高，控制该人群中HIV的感染，对遏制中国艾滋病的流行有重要意义。 |
| English Abstract: |
| Objective The prevalence of HIV/AIDS in people aged ≥ 50 years is increasing in China, resulting in another focus for AIDS prevention and control. A Meta-analysis was conducted to evaluate the HIV infection, its area and time distributions in people aged ≥ 50 years in China to provide evidence for the prevention and control of HIV/AIDS. Methods Information on HIV infection rate in people aged ≥ 50 years in China were collected from Wanfang digital database, China National Knowledge Infrastructure (CNKI), PubMed and Embase. The R Studio1.1.456 software was used to calculate the pooled infection rate, and assessed the publication bias. Results A total of 30 studies which covered 13 provinces were selected. From 2010 to 2018, the pooled HIV infection rate in people aged ≥ 50 years was 1.68% (95%CI:1.00%-2.79%). The HIV infection rate (2.60%) was higher in eastern China than in central and western China (0.16%, 2.13%). Conclusion The overall HIV infection rate in people aged ≥ 50 years is generally high in China. It is important to control the HIV infection in this population to facilitate the AIDS prevention and control in China. |
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