| 甘虹,张一,袁敏,伍晓艳,刘志荣,刘蒙,吴家兵,许韶君,龚磊,徐洪吕,陶芳标.1 052例新型冠状病毒肺炎聚集性病例流行病学特征分析[J].Chinese journal of Epidemiology,2020,41(7):1004-1008 |
| 1 052例新型冠状病毒肺炎聚集性病例流行病学特征分析 |
| Epidemiological analysis on 1 052 cases of COVID-19 in epidemic clusters |
| Received:March 01, 2020 |
| DOI：10.3760/cma.j.cn112338-20200301-00223 |
| KeyWord: 新型冠状病毒肺炎 聚集性 流行病学 |
| English Key Word: COVID-19 Clustering Epidemiology |
| FundProject:安徽医科大学新型冠状病毒感染的肺炎疫情应急科研攻关项目（YJGG202001）；安徽省科技厅、安徽省卫生健康委员会应急科研攻关项目（202004a07020002） |
| Author Name | Affiliation | E-mail | | Gan Hong | Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Key Laboratory of Population Health Across Life Cycle, Ministry of Education, Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, National Health Commission, Hefei 230032, China | | | Zhang Yi | Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Key Laboratory of Population Health Across Life Cycle, Ministry of Education, Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, National Health Commission, Hefei 230032, China | | | Yuan Min | Center for Big Data Science in Health, School Health Service Management, Anhui Medical University, Hefei 230032, China | | | Wu Xiaoyan | Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Key Laboratory of Population Health Across Life Cycle, Ministry of Education, Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, National Health Commission, Hefei 230032, China | | | Liu Zhirong | Department of Public Health Emergency Management and Acute Infectious Diseases Prevention, Anhui Provincial Center for Disease Control and Prevention, Hefei 230601, China | | | Liu Meng | Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Key Laboratory of Population Health Across Life Cycle, Ministry of Education, Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, National Health Commission, Hefei 230032, China | | | Wu Jiabing | Department of Public Health Emergency Management and Acute Infectious Diseases Prevention, Anhui Provincial Center for Disease Control and Prevention, Hefei 230601, China | | | Xu Shaojun | Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Key Laboratory of Population Health Across Life Cycle, Ministry of Education, Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, National Health Commission, Hefei 230032, China | | | Gong Lei | Department of Public Health Emergency Management and Acute Infectious Diseases Prevention, Anhui Provincial Center for Disease Control and Prevention, Hefei 230601, China1 Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Key Laboratory of Population Health Across Life Cycle, Ministry of Education, Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, National Health Commission, Hefei 230032, China | | | Xu Honglyu | Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Key Laboratory of Population Health Across Life Cycle, Ministry of Education, Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, National Health Commission, Hefei 230032, China | | | Tao Fangbiao | Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Key Laboratory of Population Health Across Life Cycle, Ministry of Education, Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, National Health Commission, Hefei 230032, China | fbtao@ahmu.edu.cn |
|
| Hits: 4671 |
| Download times: 1545 |
| Abstract: |
| 目的 了解新型冠状病毒肺炎聚集性病例的流行病学特征，探讨家庭因素以及集体活动等对本病传播的影响。方法 于2020年1月19日至2月25日每日从中国6个省份公布聚集性病例的36个地市官方平台收集积聚性病例数量、个案信息，采用描述性统计方法、χ2检验以及曲线拟合对聚集性病例的流行病学特征进行分析。结果 共收集聚集性病例366起1 052例，家庭聚集性病例占86.9%（914/1 052）；1 046例有性别信息的聚集性病例中，男性513例（49.0%），女性533例（51.0%）；病例以18～59岁青壮年为主，占68.5%（711/1 038）。在366起聚集性疫情中，有47.0%（172/366）聚集性疫情的首例确诊病例曾有武汉市或湖北省旅居史。1月19日至2月3日，首例确诊病例有武汉市或湖北省旅居史占66.5%；2月4-25日聚集性病例首例确诊病例有武汉市或湖北省旅居史仅占18.2%。一代病例与二代病例发病时间间隔M为5（2～8）d，首发病例的发病—确诊时间间隔M为6（3～9）d，续发病例的发病—确诊时间间隔M为5（3～8） d。结论 聚集性疫情在武汉市和湖北省以外多地市普遍出现，家庭密切接触是造成家庭内传播的主要原因之一。2月4日后聚集性病例以当地一代或二代以后的病例传播为主，确诊时间缩短。 |
| English Abstract: |
| Objective To understand the epidemiological characteristics of the cases of COVID-19 epidemic clusters, and explore the influence of family factors and social factors such as group activities on the spread of the disease. Methods The data of cases of COVID-19 epidemic clusters from 19 January, 2020 to 25 February, 2020 were collected from the official platforms of 36 cities in 6 provinces in China. Descriptive statistical methods, χ2 test and curve fitting were used to analyze the epidemiological characteristics of the clustered cases. Results By 25 February, 2020, the data of 1 052 cases in 366 epidemic clusters were collected. In these clustered cases, 86.9%(914/1 050) occurred in families. Among the 1 046 cases with gender information, 513 were males (49.0%) and 533 were females (51.0%). The cases were mainly young adults between 18 and 59 years old, accounting for 68.5% (711/1 038). In the 366 epidemic clusters, the clusters in which the first confirmed cases with the history of sojourn in Wuhan or Hubei accounted for 47.0%(172/366). From 19 January to 3 February, 2020, the first confirmed cases with Wuhan or Hubei sojourn history accounted for 66.5%. From 4 to 25 February, the first confirmed cases who had Wuhan or Hubei sojourn history accounted for only 18.2%. The median of interval between the first generation case onset and the second generation case onset was 5 (2-8) days. The median of onset-diagnosis interval of the initial cases was 6 (3-9) days, and the median of onset-diagnosis interval of the secondary cases was 5 (3-8) days. Conclusions Epidemic clusters of COVID-19 were common in many cities outside Wuhan and Hubei. Close contact in family was one of the main causes for the spread of household transmission of the virus. After 4 February, the epidemic clusters were mainly caused by the first generation or second generation cases in local areas, and the time for diagnosis became shorter. |
|
View Fulltext
Html FullText
View/Add Comment Download reader |
| Close |
|
|
|